T cell responses to paraphenylenediamine and to its metabolites mono- and diacetyl-paraphenylenediamine

International Archives of Allergy and Immunology

Volumn 124, Issue 1-3, 2001, Pages 356-358

  Sieben, S ^a   Kawakubo, Y ^a   Sachs, B ^a   Al Masaoudi, T ^a   Merk, H F ^a   Blömeke, Brunhilde ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Metabolism; Monoacetyl paraphenylenediamine; N,N' Diacetyl paraphenylenediamine; N Acetyltransferase 1; Paraphenylenediamine; T cell stimulation

Indexed keywords

PHENYLENEDIAMINE; PHENYLENEDIAMINE DERIVATIVE;

ACETYLATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONFERENCE PAPER; CONTACT DERMATITIS; CONTROLLED STUDY; DETOXIFICATION; HUMAN; IMMUNE RESPONSE; PATCH TEST; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035045157     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053756     Document Type: Conference Paper

References (6)

1. Lymphocyte stimulation by drug-modified microsomes
2. Dissociation of allergenic and immunogenic functions in contact sensitivity to paraphenylenediamine
3. N-Acetylation of paraphenylene-diamine in human skin and keratinocytes
4. Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4′-(acetylamino)biphenyl
5. Human N-acetylation of benzidine: Role of NAT1 and NAT2
6. Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus