Intrapulmonary pharmacokinetics of ofloxacin in drug-resistant tuberculosis

International Journal of Tuberculosis and Lung Disease

Volumn 5, Issue 3, 2001, Pages 278-282

  Chierakul, N ^a   Klomsawat, D ^a   Chulavatnatol, S ^a   Chindavijak, B ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Drug resistant tuberculosis; Fluid to serum concentration ratio; Lung epithelial lining fluid (ELF); Ofloxacin

Indexed keywords

AMIKACIN; AMINOSALICYLIC ACID; ETHAMBUTOL; KANAMYCIN; OFLOXACIN; PYRAZINAMIDE; RIFAMPICIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG SENSITIVITY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IC 50; LUNG ALVEOLUS EPITHELIUM; LUNG FLUID; LUNG LAVAGE; LUNG TUBERCULOSIS; MALE; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL;

ADULT; ANTI-INFECTIVE AGENTS; ANTITUBERCULAR AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; LUNG; MALE; OFLOXACIN; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY;

EID: 0035042657     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Activity of ciprofloxacin and other fluorinated quinolones against mycobacteria
2. Comparative in vitro activity of five fluoroquinolones against mycobacteria
3. In vitro activity of ofloxacin against Mycobacterium tuberculosis and its clinical efficacy in multiply resistant pulmonary tuberculosis
4. In vitro activities of quinolones against mycobacteria
5. Mycobacteria and new quinolones
6. Therapeutic effect of a new antibacterial substance ofloxacin (DL8280) on pulmonary tuberculosis
7. A controlled study of rifabutin and an uncontrolled study of ofloxacin in the treatment of patients with pulmonary tuberculosis resistant to isoniazid, streptomycin, and rifampicin
8. Long-term safety of ofloxacin and ciprofloxacin in the treatment of mycobacterial infections
9. Penetration of ofloxacin from blood to sputum
10. Ofloxacin concentrations in tissues involved in respiratory tract infections
11. Pharmacokinetics of levofloxacin in healthy Thai male volunteers
12. Estimation of volume of epithelial lining fluid recovered by lavage using urea as a marker of dilution
13. Microlavage: A technique for determining the volume of epithelial lining fluid
14. The host immune response to tuberculosis
15. Experimental drugs and combination therapy
16. Prospective comparative study of ofloxacin or ethambutol for the treatment of pulmonary tuberculosis
17. Ofloxacin containing combined drug regimens in the treatment of multibacillary leprosy
18. Serum pharmacokinetics of antimycobacterial drugs in patients with multidrug-resistant tuberculosis during therapy