Gastrin-releasing peptide is a potent vasodilator in humans

Clinical Pharmacology and Therapeutics

Volumn 69, Issue 4, 2001, Pages 252-259

  Clive, Sally ^a   Jodrell, Duncan ^a   Webb, David ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN RELEASING PEPTIDE; N(G) METHYLARGININE; NITROPRUSSIDE SODIUM;

ADULT; ARTICLE; BOLUS INJECTION; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FOREARM; HORMONAL REGULATION; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD FLOW; TACHYPHYLAXIS; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 0035042521     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2001.114888     Document Type: Article

References (37)

1. Neuroendocrine changes in chronic cardiac failure
2. Bombesin-like peptides and cancer
3. Mammalian bombesin-like peptides
4. Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells
5. High-affinity receptors for peptides of the bombesin family in Swiss 3T3 cells
6. High levels of intracellular bombesin characterize human small-cell lung carcinoma
7. Bombesin, somatostatin and neurotensin-like immunoreactivity in bronchial carcinoma
8. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
9. Local L-NG-monomethyl-arginine attenuates the vasodilator action of bradykinin in the human forearm
10. Comparison of forearm vasodilatation to substance P and acetylcholine: Contribution of nitric oxide
11. Biphasic forearm vascular responses to intraarterial arginine vasopressin
12. Inhibition of substance P induced vasodilation as a biological endpoint in the phase I trial of Antagonist G, a broad spectrum neuropeptide growth factor antagonist
13. Contribution of endogenous generation of endothelin-1 to basal vascular tone in man
14. The pharmacology of human blood vessels in vivo
15. An evaluation of semiautomatic blood pressure manometers against intra-arterial blood pressure
16. Effect of NG-monomethyl-L-arginine on kinin-induced vasodilation in the human forearm
17. Cyclosporine A increases nitric oxide activity in vivo
18. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
19. Effects of endotheliumoderived nitric oxide on peripheral arteriolar tone in man
20. Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes
21. The GRP test: A new clinical test of acid secretion-reproducibility data
22. Gastrin-releasing peptide: Pharmacokinetics and effects on gastro-entero-pancreatic hormones and gastric secretion in normal men
23. Human gastrin-releasing peptide: Biological potency in humans
24. Some pharmacological actions of alytesin and bombesin
25. Cardiovascular pharmacology of bombesin, a new polypeptide from amphibian skin
26. Responses of the rat cardiovascular system to substance P, neurotensin and bombesin
27. Bombesin and substance P modulate peripheral sympathetic and cardiovascular activity
28. Vasodilation by calcitonin gene-related peptide and by substance P: A comparison of their effects on resistance and capacitance vessels of human forearms
29. Hormone interactions in the isolated rabbit heart: Synthesis and vasomotor effects of prostaglandins, angiotensin and bradykinin
30. Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm
31. Arachidonic acid release by bombesin: A novel postreceptor target for heterologous mitogenic desensitization
32. Sucralfate suppresses Helicobacter pylori infection and reduces gastric acid secretion by 50% in patients with duodenal ulcer
33. Endocrine responses to exogenous bombesin and gastrin-releasing peptide in conscious calves
34. Pulmonary vascular effects of bombesin and gastrin-releasing peptide in conscious newborn lambs
35. A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro
36. Growth of small cell lung cancer cells: Stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo
37. Preclinical studies on the broad-spectrum growth factor, Antagonist G