Search for Drosophila caspases bears fruit: STRICA enters the fray

Cell Death and Differentiation

Volumn 8, Issue 4, 2001, Pages 319-323

  Adrain, C ^a   Martin, S J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CYTOKINE; DREDD CASPASE; DRONC CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; SERINE; SERINE THREONINE RICH CASPASE; THREONINE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELISH; UNCLASSIFIED DRUG;

APOPTOSIS; DROSOPHILA; EDITORIAL; ENZYME ACTIVITY; FLY; GRAM NEGATIVE INFECTION; HUMAN; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GRAM-NEGATIVE BACTERIAL INFECTIONS; INSECT PROTEINS; MEMBRANE GLYCOPROTEINS; MODELS, BIOLOGICAL; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTORS;

NEGIBACTERIA;

EID: 0035040769     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400869     Document Type: Editorial

References (38)

1. Serial killers: Ordering caspase activation events in apoptosis
2. The fly caspases
3. Caspases: The executioners of apoptosis
4. Caspase knockouts: Matters of life and death
5. Divinations and surprises: Genetic analysis of caspase function in mice
6. Cell death regulation in Drosophila: Conservation of mechanism and unique insights
7. Understanding IAP function and regulation: A view from Drosophila
8. STRICA, a novel Drosophila caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2
9. DCP-1, a Drosophila cell death protease essential for development
10. drlCE is an essential caspase required for apoptotic activity in Drosophila cells
11. DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7
12. Biochemical and genetic interactions between Drosophila caspases and the proapoptotic genes rpr, hid, and grim
13. Identification of a Drosophila melanogaster ICE/ CED-3-related protease, drlCE
14. drlCE is an essential caspase required for apoptotic activity in Drosophila cells
15. Identification and developmental expression of inhibitor of caspase-activated DNase (ICAD) in Drosophila melanogaster
16. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
17. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM
18. Prodomains, adaptors, oligomerization: The pursuit of caspase activation in apoptosis
19. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32
20. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
21. DRONC, an ecdysone-inducible Drosophila caspase
22. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
23. DARK is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway
24. Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator
25. HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
26. An essential role for the caspase dronc in developmentally programmed cell death in Drosophila
27. Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes
28. Altered cytochrome c display precedes apoptotic cell death in Drosophila
29. dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD
30. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
31. DREDD, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila
32. Death receptors: Signaling and modulation
33. Activation of the Drosophila NF-kB factor Relish by rapid endoproteolytic cleavage
34. The Drosophila caspase DREDD is required to reisit Gram-negative bacterial infection
35. Activation of NF-kappaB by FADD, Casper, and caspase-8
36. Purification and characterization of active human interleukin-1 beta-converting enzyme from THP. 1 monocytic cells
37. Scythe: A novel reaper-binding apoptotic regulator
38. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death