Crystal structure of proteolytic fragments of the redox-sensitive hsp33 with constitutive chaperone activity

Nature Structural Biology

Volumn 8, Issue 5, 2001, Pages 459-466

  Kim, S J ^a   Jeong, D G ^a   Chi, S W ^a   Lee, J L ^a   Ryu, S E ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CYSTEINE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 33; UNCLASSIFIED DRUG; ZINC;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DISSOCIATION; HYDROPHOBICITY; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; CHROMATOGRAPHY, GEL; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIMERIZATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HEAT-SHOCK PROTEINS; MODELS, MOLECULAR; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SEQUENCE DELETION; ULTRACENTRIFUGATION; ZINC;

EID: 0035037448     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/87639     Document Type: Article

References (38)

1. An essential role for free radicals and derived species in signal transduction
2. Role of redox potential and reactive oxygen species in stress signaling
3. Chaperone activity with a redox switch
4. Oxidative stress: Protein folding with a novel redox switch
5. Mass spectrometry unravels disulfide bond formation as the mechanism that activates a molecular chaperone
6. Phase determination from multiwavelength anomalous diffraction measurements
7. Crystal structure of the Aequorea victoria green fluorescent M. et al protein
8. Implication of tubby proteins as transcription factors by structure-based functional analysis
9. 7 chaperone complex
10. Crystal structure of a small heat-shock protein
11. Structural analysis of substrate binding by the molecular chaperone DnaK
12. Structure-function studies on small heat shock protein oligomeric assembly and interaction with unfolded polypeptides
13. Heat-induced oligomerization of the molecular chaperone Hsp90. Inhibition by ATP and geldanamycin and activation by transition metal oxyanions
14. Oligomer formation by 3D domain swapping: A model for protein assembly and misassembly
15. Refined structure of monomeric diphtheria toxin at 2.3 Å resolution
16. The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins
17. A novel dimer configuration revealed by the crystal structure at 2.4 Å resolution of human interleukin-5
18. Hsp33's redox switch has a novel zinc-binding motif
19. Bridge over troubled waters: Sensing stress by disulfide bond formation
20. Activation of the OxyR transcription factor by reversible disulfide bond formation
21. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
22. Redox-dependent shift of OxyR-DNA contacts along an extended DNA-binding site: A mechanism for differential promoter selection
23. Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
24. Structural basis of the redox switch in the OxyR transcription factor
25. Processing of X-ray diffraction data collected in oscillation mode
26. Automated structure solution for MIR and MAD
27. Crystallography & NMR system (CNS): A new software system for macromolecular structure determination
28. Improved methods for building protein models in electron density maps and the location of errors in these models
29. PROCHECK: A program to check the stereochemical quality of protein structures
30. Ribbons
31. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
32. An extensively modified version of MolScript that includes greatly enhanced colouring capabilities
33. Defining the structure and stability of macromolecular assemblies in solution: The re-emergence of analytical ultracentrifugation as a practical tool
34. Calculation of protein extinction coefficients from amino acid sequence data
35. CLUSTALW: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
36. ALSCRIPT: A tool to format multiple sequence alignments
37. Protein folding and association: Insights from the interracial and thermodynamic properties of hydrocarbons