Clinical significance of enzyme-linked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies in patients with bullous pemphigoid

Journal of Dermatological Science

Volumn 26, Issue 1, 2001, Pages 14-18

  Amo, Yasuyuki ^a   Ohkawa, Tsukasa ^a   Tatsuta, Minako ^a   Hamada, Yuhko ^a   Fujimura, Takao ^a   Katsuoka, Kensei ^a   Hashimoto, Takashi ^b  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autoantibody; BP180; Bullous pemphigoid; Recombinant protein

Indexed keywords

AUTOANTIBODY; BETAMETHASONE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; DAPSONE; MINOCYCLINE; RECOMBINANT PROTEIN;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; BLISTER; CLINICAL ARTICLE; DISEASE ACTIVITY; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; MALE; PEMPHIGOID; PLASMAPHERESIS; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; AUTOANTIBODIES; AUTOANTIGENS; BIOLOGICAL MARKERS; CARRIER PROTEINS; COLLAGEN; CYTOSKELETAL PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; NON-FIBRILLAR COLLAGENS; PEMPHIGOID, BULLOUS; PREDICTIVE VALUE OF TESTS; RECOMBINANT PROTEINS;

EID: 0035037064     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-1811(00)00149-3     Document Type: Article

References (10)

1. A highly sensitive enzyme-linked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies in patients with bullous pemphigoid
2. A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180
3. The majority of bullous pemphigoid and herpes gestationis serum samples react with the NC16a domain of the 180-kDa bullous pemphigoid antigen
4. Development of ELISA to detect anti-BP180 autoantibodies in bullous pemphigoid and herpes gestationis
5. Immunoreactivity of bullous pemphigoid (BP) autoantibodies against the NC16A and C-terminal domains of the 180 kDa BP antigen (BP180): immunoblot analysis and enzyme-linked immunosorbent assay using BP180 recombinant proteins
6. Bullous pemphigoid and herpes gestationis autoantibodies recognized a common non-collagenous site on the BP180 ectodomain
7. A critical role for neutrophil elastase in experimental bullous pemphigoid
8. Bullous pemphigoid: clinical and immunologic follow-up after successful therapy
9. The interleukin-2 receptor in lesions and serum of bullous pemphigoid
10. Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid