Pharmacokinetics of lactosaminated recombinant human growth hormone in mice

Acta Pharmacologica Sinica

Volumn 22, Issue 5, 2001, Pages 450-454

  Li, Yun Chun ^a   Guan, Chang Tian ^a   Zhao, Ke Qing ^b   Chen, Ze Lian ^a   Li, Tong Ling ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN NORMAL UNIVERSITY   (China)

Author keywords

Pharmacokinetics; Recombinant proteins; Somatotropin

Indexed keywords

GROWTH HORMONE DERIVATIVE; HUMAN GROWTH HORMONE; LACTOSAMINATED RECOMBINANT HUMAN GROWTH HORMONE; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; LIVER; MEAN RESIDENCE TIME; MOUSE; NONHUMAN; RADIOIMMUNOASSAY;

AMINO SUGARS; ANIMALS; GROWTH HORMONE; LIVER; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION;

EID: 0035036560     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Growth hormone and liver
2. Intravenous growth hormone: Growth responses to patterned infusions in hypophysectomized rats
3. Role of growth hormone in fluid homeostasis
4. Evaluation of livertaxis mechanism of galactosyl-human growth hormone
5. Research on receptor targeting drugs of chemotherapy of viral hepatitis I. Synthesis of lactosaminated serum albumin and its conjugate with adenine arabinoside monophosphate
6. Drug targeting in antiviral chemotherapy
7. Comparative study on livertaxis of lactosaminated human growth hormone and galactosyl-human growth hormone
8. Different effects of intermittent and continuous growth hormone (GH) administration on serum somatomedin-C/insulin-like growth factor 1 and liver GH receptors in hypophysectomized rats
9. Our experience with quality control in current growth hormone assays