Specific changes to the mechanism of cell locomotion induced by overexpression of β-actin

Journal of Cell Science

Volumn 114, Issue 7, 2001, Pages 1367-1377

  Peckham, Michelle ^a   Miller, Gaynor ^a   Wells, Claire ^b   Zicha, Daniel ^c   Dunn, Graham A ^d  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c Imperial Cancer Research Fund   (United States)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Cell adhesion; Cell Movement; Cell polarity; Interference microscopy; Microfilament

Indexed keywords

ACTIN BINDING PROTEIN; BETA ACTIN; DIACETYL OXIME; MYOSIN;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; CROSS LINKING; GENE OVEREXPRESSION; LEUKOCYTE; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CONTRACTILE PROTEINS; DIACETYL; GENE EXPRESSION; HUMANS; MICE; MICROFILAMENT PROTEINS; MYOSINS; PROFILINS; THYMOSIN;

ANIMALIA;

EID: 0035035708     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Bereiter-Hahn, J. and Luers, H. (1998). Subcellular tension fields and mechanical resistance of the lamella front related to the direction of locomotion. Cell. Biochem. Biophys. 29, 243-262.
2. Brown, A. F. and Dunn, G. A. (1989). Microinterferometry of the movement of dry matter in fibroblasts. J. Cell Sci. 92, 379-89.
3. Chen, W. T. (1979). Induction of spreading during fibroblast movement. J. Cell Biol. 81, 684-691.
4. Chen, W. T. (1981). Mechanism of retraction of the trailing edge during fibroblast movement. J. Cell Biol. 90, 187-200.
5. Clark, P., Coles, D. and Peckham, M. (1997). Preferential adhesion to and survival on patterned laminin organizes myogenesis in vitro. Exp. Cell Res. 230, 275-283.
6. Condeelis, J. (1993). Life at the leading edge: the formation of cell protrusions. Annu. Rev. Cell Biol. 9, 411-444.
7. Cramer, L. P. and Mitchison, T. J. (1995). Myosin is involved in postmitotic cell spreading. J. Cell Biol. 131, 179-89.
8. Cunningham, C. C. (1995). Actin polymerization and intracellular solvent flow in cell surface blebbing. J. Cell Biol. 129, 1589-1599.
9. Dunn, G. A. (1980). Mechanisms of fibroblast locomotion. In Cell Adhesion and Motility. 3rd Symposium of the British Society for Cell Biology (ed. A. S. G. Curtis and J. D. Pitts), pp. 409-423. Cambridge: Cambridge University Press.
10. Dunn, G. A., Weber, I. and Zicha, D. (1997a). Protrusion, retraction and the efficiency of cell locomotion. In Dynamics of Cell and Tissue Motion (ed. W. Alt, A. Deutsch and G. A. Dunn), pp. 33-46. Birkhäuser, Basel.
11. Dunn, G. A. and Zicha, D. (1995). Dynamics of fibroblast spreading. J. Cell Sci. 108, 1239-1249.
12. Leavitt, J., Gunning, P., Porreca, P., Ng, S. Y., Lin, C. S. and Kedes, L. (1984). Molecular cloning and characterization of mutant and wild-type human beta-actin genes. Mol. Cell. Biol. 4, 1961-1969.
13. Lloyd, C., Schevzov, G. and Gunning, P. (1992). Transfection of nonmuscle beta- and gamma-actin genes into myoblasts elicits different feedback regulatory responses from endogenous actin genes. J. Cell Biol. 117, 787-797.