Suppressive effects of adenosine on the 5-lipoxygenase pathway in human polymorphonuclear leukocytes

Drug Development Research

Volumn 52, Issue 1-2, 2001, Pages 397-405

  Flamand, Nicolas ^a   Plante, Hendrick ^a   Picard, Serge ^a   Austin, Michelle ^a   Surette, Marc E ^a   Krump, Eéric ^a   Bourgoin, Sylvain ^a   Borgeat, Pierre ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Arachidonate; cAMP; Eicosanoid; Inflammation; Leukocyte; Leukotriene; Phospholipase

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE; ARACHIDONATE 5 LIPOXYGENASE; CHEMOATTRACTANT; CYCLIC AMP; CYTOKINE; LEUKOTRIENE; PROSTAGLANDIN E;

ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; CALCIUM TRANSPORT; CONFERENCE PAPER; DOWN REGULATION; HOST RESISTANCE; INFLAMMATION; NEUTROPHIL; PROTEIN TRANSPORT;

EID: 0035029044     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1140     Document Type: Conference Paper

References (2)

1. Alves AC, Pires AL, Cruz HN, Serra MF, Diaz EL, Cordeiro RS, Lagente V, Martins MA. 1996. Selective inhibition of phosphodiesterase type IV suppresses the chemotactic responsiveness of rat eosinophils in vitro. Eur J Pharmacol 312:89-96.
2. Anderson R, Visser SS, Ramafi G, Theron AJ. 2000. Accelerated resequestration of cytosolic calcium and suppression of the pro-in-flammatory activities of human neutrophils by CGS-21680. Br J Pharmacol 130:717-724.