Expression of MIB and BCL-2 in patients with nephrogenic rests with and without associated wilms' tumors

European Journal of Pediatric Surgery

Volumn 11, Issue 2, 2001, Pages 105-109

  Wunsch L ^a   Flemming, P ^a   Gluer S ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Bcl 2 expression; Nephroblastomatosis; Nephrogenic rests

Indexed keywords

KI 67 ANTIGEN; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; KIDNEY PARENCHYMA; MALE; NEPHROBLASTOMA; PROTEIN EXPRESSION; TUMOR GROWTH;

CHILD, PRESCHOOL; FEMALE; GENES, BCL-2; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; KI-67 ANTIGEN; KIDNEY NEOPLASMS; MALE; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS C-BCL-2; WILMS TUMOR;

EID: 0035028536     PISSN: 09397248     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-13783     Document Type: Article

References (8)

1. Precursor lesions of Wilms tumors: Clinical and biological implications
2. Proliferation and maturation indices in nephrogenic rests and Wilms tumors; the emergence of heterogeneity from dormant nodular renal blastema
3. Microdissecting the genetic events in nephrogenic rests and Wilms tumor development
4. Regulation of the proto-oncogen bcl-2 and c-myc by the Wilms tumor suppression gene WT1
5. Expression of bcl-2 in fetal tissues suggests a role in morphogenesis
6. Expression of bcl-2 onco-protein in renal cell tumors
7. Blastemal cells of the nephroblastomatosis complex share an onco-developmental antigen with embryonic kidney and Wilms tumor