Rupture of a previously normal spleen in association with enoxaparin: An unusual cause of shock

Journal of Emergency Medicine

Volumn 20, Issue 4, 2001, Pages 349-352

  Burg, Michael David ^a,b   Dallara, John James ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b University Medical Center Fresno   (United States)

Author keywords

Enoxaparin; Low molecular weight heparin; Shock; Spleen; Splenic rupture

Indexed keywords

ENOXAPARIN;

ADULT; ARTICLE; CASE REPORT; HUMAN; MALE; PRIORITY JOURNAL; SHOCK; SPLEEN RUPTURE;

ANTICOAGULANTS; DIAGNOSIS, DIFFERENTIAL; ENOXAPARIN; HUMANS; INJECTIONS, SUBCUTANEOUS; LAPAROTOMY; MALE; MIDDLE AGED; RISK FACTORS; SHOCK; SPLENIC RUPTURE;

EID: 0035026573     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-4679(01)00310-9     Document Type: Article

References (22)

1. Buciuto R, Kald A, Borch, K. Spontaneous rupture of the spleen. Eur J Surg 1992;158:129-30.
2. Kumar S, Gupta A, Shrivastava U, Mathur, S. Spontaneous rupture of normal spleen: an enigma recalled. Br J Clin Pract 1992;46: 67-8.
3. Lambert G, Cook P, Gardiner G, Regan J. Spontaneous splenic rupture associated with thrombolytic therapy and/or concomitant heparin anticoagulation. Cardiovasc Intervent Radiol 1992;15:177-9.
4. Baker A, Adair, N. Acute hypercapnia and hemodynamic collapse in a 54-year-old man. Chest 1995;108:266-8.
5. Blaivas M, Quinn J. Diagnosis of spontaneous splenic rupture with emergency ultrasonography. Ann Emerg Med 1998;32: 627-30.
6. Toussi H, Cross K, Sheehan S, Bouchier-Hayes D, Leahy A. Spontaneous splenic rupture: a rare complication of acute pancreatitis. Br J Surg 1996;83:632.
7. Lieberman M, Levitt M. Spontaneous rupture of the spleen: a case report and literature review. Am J Emerg Med 1989;7:28-31.
8. Linhart N, Laforest M, Guiraud-Vitaux F, et al. Pharmacokinetics and tissue distribution of 99mTc-labelled enoxaparin in the rat: evaluation of dosimetry parameters. Biomed Pharmacother 1990; 44:317-23.
9. Wakefield T, Andrews P, Wrobleski S, et al. Reversal of low-molecular-weight heparin anticoagulation by synthetic protamine analogues. J Surg Res 1994;56:586-93.
10. Bang C, Berstad A, Talstad I. Incomplete reversal of enoxaparin-induced bleeding by protamine sulfate. Haemostasis 1991;21:155-60.
11. PDR.net. http://physician.pdr.net/physician/psrecord.htm? NS doc offset=0&NS doc returned=2&NS adv search=0&NS search set=ivaTOfYZ b92302809286f7&NS template dir=&NS initial frm=l. Date accessed: 4/15/00.
12. Hynson J, Katz J, Bueff H. Epidural hematoma associated with enoxaparin. Anesth Analg 1996;82:1072-5.
13. Antonelli D, Fares L, Anene C. Enoxaparin associated with huge abdominal wall hematomas: a report of two cases. Am Surg 2000;66:797-800.
14. Montoya J, Pokala N, Melde S. Retroperitoneal hematoma and enoxaparin. Ann Intern Med 1999;131:796-7.
15. Houde J, Steinberg G. Intrahepatic hemorrhage after use of low-molecular-weight heparin for total hip arthroplasty. J Arthroplasty 1999;14:372-4.
16. McLaughlin J, Paulson M, Rosenthal R. Delayed onset of anterior tibial compartment syndrome in a patient receiving low-molecular-weight heparin. A case report. J Bone Joint Surg Am 1998;80: 1789-90.
17. Klein S, D'Ercole F, Greengrass R, Warner D. Enoxaparin associated with psoas hematoma and lumbar plexopathy after lumbar plexus block. Anesthesiology 1997;87:1576-9.
18. Barratt S, Ruff S, Edwards R. Heparin-induced thrombocytopenia presenting after the cessation of low molecular weight heparin prophylaxis with enoxaparin. Med J Aust 2000;172:449.
19. Mendez J, Sanchis M, de la Fuente R, et al. Delayed-type hyper-sensitivity to subcutaneous enoxaparin. Allergy 1998;53: 999-1003.
20. Gerlach A, Pickworth K, Seth S, Tanna S, Barnes J. Enoxaparin and bleeding complications: a review in patients with and without renal insufficiency. Pharmacotherapy 2000;20:771-5.
21. Blankenship J, Indeck M. Spontaneous splenic rupture complicating anticoagulant or thrombolytic therapy. Am J Med 1993;94: 433-7.
22. Wergowshe G, Carmody, T. Splenic rupture from coughing. Arch Surg 1983;118:1227.