Growth factor-stimulated protein synthesis is inhibited by sodium orthovanadate

European Journal of Biochemistry

Volumn 268, Issue 8, 2001, Pages 2308-2314

  Viñals, Francesc ^a,b   McKenzie, Fergus R ^a   Pouysségur, Jacques ^a  

^a CENTRE DE BIOCHIMIE   (France)

^b Unitat de Bioquimica   (Spain)

Author keywords

Akt; Growth factors; Orthovanadate; p42 p44 MAPK; Protein synthesis

Indexed keywords

GENE PRODUCT; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; PROTEIN MKP 1; PROTEIN P42; PROTEIN P44; S6 KINASE; UNCLASSIFIED DRUG; VANADATE SODIUM;

ANIMAL CELL; ARTICLE; DNA SYNTHESIS; DRUG EFFECT; ENZYME ACTIVATION; IC 50; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-4E; FIBROBLAST GROWTH FACTOR 2; GROWTH SUBSTANCES; IMMEDIATE-EARLY PROTEINS; INHIBITORY CONCENTRATION 50; PEPTIDE INITIATION FACTORS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-FOS; SEPHAROSE; SIGNAL TRANSDUCTION; THROMBIN; TIME FACTORS; VANADATES;

ANIMALIA; BOVINAE;

EID: 0035022488     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02108.x     Document Type: Article

References (30)

1. Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate
2. Phosphotyrosyl-protein phosphatase of TCRC-2 cells
3. An acid phosphatase in the plasma membranes of human astrocytoma showing marked specificity toward phosphotyrosine protein
4. Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins
5. Purification and characterization of a 40S ribosomal protein S6 kinase from vanadate-stimulated Swiss 3T3 cells
6. Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor or protein tyrosine phosphatases
7. Activation of mitogen-activated protein (MAP) kinase pathway by pervanadate, a potent inhibitor of tyrosine phosphatases
8. Perspective in diabetes: Insulin-mimetic effects of vanadate: Possible implications for future treatment of diabetes
9. Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes
10. Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle
11. Activation of mesangial cells by the phosphatase inhibitor vanadate
12. Control of muscle differentiation in BC3H1 cells by fibroblast growth factor and vanadate
13. Regulation of translation initiation and modulation of cellular physiology
14. A signaling pathway to translational control
15. Translational initiation: Adept at adapting
16. Animal cell cycles and their control
17. The phos-phorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
18. Involvement of stress-activated protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells
19. Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5(0)-cap function
20. The mRNA 5(0)cap-binding protein eIF4E and control of cell growth
21. PHAS/4(E)-BPs as regulators of mRNA translation and cell proliferation
22. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44 MAPK cascade
23. PHAS-I as a link between mitogen-activated protein kinase and translation initiation
24. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
25. Transcriptional regulation by extracellular signals: Mechanisms and specificity
26. Inhibition of eukaryotic protein chain initiation by vanadate
27. Protein phosphatase 2A interacts with the 70 kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein
28. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
29. Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F
30. Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors