Approach to the diagnosis of thin basement membrane nephropathy in females with the use of antibodies to type IV collagen

Archives of Pathology and Laboratory Medicine

Volumn 125, Issue 5, 2001, Pages 631-636

  Lajoie, Ginette ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; COLLAGEN TYPE 4;

ADULT; ALPHA CHAIN; ALPORT SYNDROME; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CLINICAL ARTICLE; CLINICAL TRIAL; DIFFERENTIAL DIAGNOSIS; FAMILY HISTORY; FEMALE; GLOMERULUS BASEMENT MEMBRANE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY FAILURE; PHYSICAL EXAMINATION; STAINING; X CHROMOSOME LINKED DISORDER;

ADULT; ANTIBODIES, MONOCLONAL; BASEMENT MEMBRANE; COLLAGEN; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; KIDNEY GLOMERULUS; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; NEPHRITIS, HEREDITARY;

EID: 0035022289     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Dische FE, Andersen VE, Keane SJ, Taube D, Bewick M, Parsons V. Incidence of thin basement membrane nephropathy: morphometric investigation of a population sample. J Clin Pathol. 1990;43:457-460.
2. Tiebosch ATMG, Frederik PM, van Breda Vriesman PJC, et al. Thin-basement-membrane nephropathy in adults with persistent hematuria. N Engl J Med. 1989;320:14-18.
3. Bodziak KA, Hammond WS, Molitoris BA. Inherited diseases of the glomerular basement membrane. Am J Kidney Dis. 1994;23:605-618.
4. Kashtan CE. Alport syndrome and thin glomerular basement membrane disease. J Am Soc Nephrol. 1998;9:1736-1750.
5. Dische FE, Weston MJ, Parsons V. Abnormally thin glomerular basement membranes associated with hematuria, proteinuria or renal failure in adults. Am J Nephrol. 1985;5:103-109.
6. Nieuwhof CMG, de Heer F, de Leeuw P, van Breda Vriesman PJC. Thin GBM nephropathy: premature glomerular obsolescence is associated with hypertension and late onset renal failure. Kidney Int. 1997;51:1596-1601.
7. Gregory MC, Terreros DA, Barker DF, Fain PN, Denison JC, Atkin CL. Alport syndrome: clinical phenotypes, incidence, and pathology. Contrib Nephrol. 1996;117:1-28.
8. Kashtan CE, Michael AF. Alport syndrome: from bedside to genome to bedside. Am J Kidney Dis. 1993;22:627-640.
9. Kashtan CE, Michael AF. Alport syndrome. Kidney Int. 1996;50:1445-1463.
10. Pirson Y. Making the diagnosis of Alport's syndrome. Kidney Int. 1999;56: 760-775.
11. Dische FE. Measurement of glomerular basement membrane thickness and its application to the diagnosis of thin-membrane nephropathy. Arch Pathol Lab Mod. 1992;116:43-49.
12. Johansson C, Butkowski R, Wieslander J. Characterization of monoclonal antibodies to the globular domain of collagen IV. Connect Tissue Res. 1991;25: 229-241.
13. Kleppel MM, Fan WW, Cheong HI, Kashtan CE, Michael AF. Immunochemical studies of the Alport antigen. Kidney Int. 1992;41:1629-1637.
14. Ding J, Kashtan CE, Fan WW, et al. A monoclonal antibody marker for Alport syndrome identifies the Alport antigen as the α5 chain of type IV collagen. Kidney Int. 1994;46:1504-1506.
15. Kleppel MM, Santi PA, Cameron JD, Wieslander J, Michael AF. Human tissue distribution of novel basement membrane collagen. Am J Pathol. 1989;134: 813-825.
16. Yoshioka K, Michael AF, Velosa J, Fish AJ. Detection of hidden nephritogenic antigen determinants in human renal and nonrenal basement membranes. Am J Pathol. 1985;121:156-165.
17. Meleg-Smith S, Magliato S, Cheles M, Garola RE, Kashtan CE. X-linked Alport syndrome in females. Hum Pathol. 1998;29:404-408.
18. Hill GS, Jenis EH, Goodloe S. The nonspecificity of the ultrastructural alterations in hereditary nephritis. Lab Invest. 1974;31:516-532.
19. Nakanishi K, Yoshikawa N, lijima K, etal. Immunohistochemical study of α1-5 chains of type IV collagen in hereditary nephritis. Kidney Int. 1994;46: 1413-1421.
20. Lemmink HH, Nillesen WN, Mochizuki T, et al. Benign familial hematuria due to mutation of the type IV collagen α4 gene. J Clin Invest. 1996;98:1114-1118.
21. Buzza M, Wilson D, Savige J. Linkage of thin basement membrane disease (TBMD) to the loci for X-linked and autosomal recessive Alport syndrome [abstract]. J Am Soc Nephrol. 1998;9:387A.
22. Saito A, Yamazaki H, Nakagawa Y, Arakawa M. Molecular genetics of renal diseases. Intern Mod. 1997;36:81-86.
23. Nomura S, Naito I, Fukushima T, et al. Molecular genetics and immunohistochemical study of autosomal recessive Alport's syndrome. J Am Kidney Dis. 1998;31:E4.
24. Heikkilä P, Tryggvason K, Thorner P. Animal models of Alport syndrome: advancing the prospects for effective human gene therapy. Exp Nephrol. 2000;8: 1-7.