Both retinoic acid and 1, 25(OH)2 vitamin D3 inhibit thyroid hormone-induced terminal differentiation of growth plate chondrocytes

Journal of Orthopaedic Research

Volumn 19, Issue 1, 2001, Pages 43-49

  Ballock, R Tracy ^a   Zhou, Xiaolan ^a   Mink, Lynn M ^a   Chen, Daniel H C ^a   Mita, Barry C ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COLLAGEN; DIMERS; DNA; GENES; HORMONES; ORGANIC ACIDS; RNA; VITAMINS;

NUCLEAR HORMONE RECEPTORS;

ORTHOPEDICS;

ALKALINE PHOSPHATASE; CALCITRIOL; CELL NUCLEUS RECEPTOR; COLLAGEN TYPE 10; DIMER; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HORMONE RECEPTOR; LIOTHYRONINE; MESSENGER RNA; RETINOIC ACID; RETINOIC ACID RECEPTOR; THYROID HORMONE; THYROID HORMONE RECEPTOR; VITAMIN D; VITAMIN D RECEPTOR;

ANIMAL CELL; ARTICLE; BONE MATURATION; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CLINICAL OBSERVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE EXPRESSION; GENE TARGETING; GROWTH PLATE; HYPOTHESIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; TARGET CELL; TRANSCRIPTION REGULATION;

EID: 0035022041     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(00)00024-3     Document Type: Article

References (46)

1. Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10
2. Inhibition of the chondrocyte phenotype by retinoic acid involves upregulation of metalloprotease genes independent of TGF-β
3. TGF-β 1 prevents hypertrophy of epiphyseal chondrocytes: Regulation of gene expression for cartilage matrix proteins and metalloproteases
4. Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium
5. Nongenomic regulation of extracellular matrix events by vitamin D metabolites
6. The effects of vitamin D metabolites on the plasma and matrix vesicle membranes of growth and resting cartilage cells in vitro
7. In vitro studies on the regulation of endochondral ossification by vitamin D
8. Hypertrophic chondrocytes undergo further mineralization in culture
9. 3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers
10. Genomic sequencing
11. In vivo effect of 1, 25-dihydroxycholecalciferol on the proliferation and differentiation of avian chondrocytes
12. 3 treated non-hypertrophic chondrocytes
13. 3 on induction of chondrocyte maturation in culture extracellular matrix gene expression and morphology
14. Bone morphogenetic protein-7 in growth plate chondrocytes regulation by retinoic acid is dependent on the stage of chondrocyte maturation
15. Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture
16. Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXRB) enhances DNA binding and TH-dependent transcriptional activation
17. Retinoic acid rapidly reduces cartilage matrix synthesis by altering gene transcription in chondrocytes
18. 3 in primary cultured hypertrophic chondrocytes
19. Responsiveness to retinoic acid changes during chondrocyte maturation
20. Retinoic acid Induces rapid mineralization and expression of mineralization-related genes in chondrocytes
21. Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes regulation by transforming growth factor B and serum factors
22. Role of 1, 25-dihydroxycholecalciferol in growth-plate cartilage. Inhibition of terminal differentiation of chondrocytes in vitro and in vivo
23. 3
24. 3 signalling
25. 3
26. Recombinant thyroid hormone receptor and retinoid X receptor stimulate ligand-dependent transcription in vitro
27. 3 receptor and other nonreceptor transcription factors
28. Protein measurement with the Folin phenol reagent
29. Positive and negative regulation of retinoid X receptor gene expression by thyroid hormone in the rat
30. Type X collagen gene expression is transiently upregulated by retinoic acid treatment in chick chondrocyte cultures
31. Retinoic acid treatment induces type X collagen gene expression in cultured chick chondrocytes
32. Focal retardation and arrestment of growth of bones due to vitamin A intoxication
33. Determinants for selective RAR and TR recognition of direct repeat HRE'S
34. Matrix-induced endochondral bone differentiation influence of hypophysectomy, growth hormone, and thyroid-stimulating hormone
35. Expression of type X collagen is transiently stimulated in redifferentiating chondrocytes pretreated with retinoic acid
36. Specificity and flexibility of vitamin D signaling
37. 3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors
38. 3-responsive alkaline phosphatase in cultures chondrocytes
39. 3 on growth zone and resting zone chondrocyte membrane alkaline phosphatase and phospholipase-A2 specific activities
40. Effect of retinoic acid on proliferation and differentiation of cultured chondrocytes in terminal differentiation
41. Structure and expression of the rat osteosarcoma (ROS 17/28) alkaline phosphatase. Product of a single copy gene
42. 3 receptors
43. Pathogenesis of vitamin (A and D)-induced premature growth-plate closure in calves
44. Effect of osteogenic protein-1 on the development and mineralization of primary cultures of growth plate chondrocytes. Modulation by retinoic acid
45. Retinoic acid stimulates matrix calcification and initiates type I collagen synthesis in primary cultures of avian weight-bearing growth plate chondrocytes
46. RXRβ. A Coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements