Oral shark cartilage does not abolish carcinogenesis but delays tumor progression in a murine model

Anticancer Research

Volumn 21, Issue 2 A, 2001, Pages 1065-1070

  Barber, R ^a   Delahunt, B ^a   Grebe, S K G ^a   Davis, P F ^a   Thornton, A ^a   Slim, G C ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Angiogenesis; Renal cell carcinoma; Shark cartilage; Streptozotocin

Indexed keywords

ANTINEOPLASTIC AGENT; SHARK CARTILAGE EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; FEMALE; KIDNEY DYSPLASIA; KIDNEY EPITHELIUM; KIDNEY TUMOR; MOUSE; NONHUMAN; PAPILLOMA; PRIORITY JOURNAL; SOLID TUMOR;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CARTILAGE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; KIDNEY NEOPLASMS; MICE; MICE, INBRED CBA; SHARKS; STREPTOZOCIN;

EID: 0035021842     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. The application of shark cartilage in the treatment of cancer
2. Tumour associated angiogenesis: Mechanisms, clinical implications and therapeutic strategies
3. Phase I/II trial of the safety and efficacy of shark cartilage in the treatment of advanced cancer
4. Proliferation kinetics of streptozotocin-induced renal tumours in mice
5. Angiogenesis inhibitors and their delivery systems
6. Identification of an inhibitor of neovascularization from cartilage
7. Shark cartilage contains inhibitors of tumor angiogenesis
8. A novel angiogenic inhibitor derived from Japanese shark cartilage (I). Extraction and estimation of inhibitory activities toward tumor and embryonic angiogensis
9. Antiproliferative activity of shark cartilage with and without tumor necrosis factor-alpha in human umbilical vein endothelium
10. Skeptics of oral administration of shark cartilage
11. Inhibition of angiogenesis by oral ingestion of powdered shark cartilage in a rat model
12. Antiangiogenic effects of the oral administration of liquid cartilage extracts in humans
13. Shark cartilage extract interferes with cell adhesion and induces reorganization of focal adhesions in cultured endothelial cells
14. The effect of shark cartilage extracts on the growth and metastatic spread of SCCVII carcinoma
15. Effect of U-995 a potent shark cartilage-derived angiogenesis inhibitor on anti-angiogenesis and anti-tumor activities
16. Long term isografts of cultured fetal mouse pancreatic islets. The oncogenic effects of streptozotocin and the prevention of diabetic renal complications
17. Identification of a high-frequency model for renal carcinoma by the induction of renal tumors in the mouse with a single dose of streptozotocin
18. Ultrastructure of streptozotocin-induced renal tumours in mice