Gestational retinoic acid exposure in the rat: Effects of sex, strain and exposure period

Neurotoxicology and Teratology

Volumn 23, Issue 2, 2001, Pages 147-156

  Holson, R Robert ^a   Cogan, Jennifer E ^a   Adams, Jane ^b  

^a NEW MEXICO INSTITUTE OF MINING AND TECHNOLOGY   (United States)

^b UNIVERSITY OF MASSACHUSETTS BOSTON   (United States)

Author keywords

Cerebellum; Prenatal effects; Retinoids; Strain differences; Surface righting; Vermis

Indexed keywords

RETINOIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN STEM; BRAIN WEIGHT; CEREBELLUM VERMIS; CONTROLLED STUDY; COVARIANCE; DOSE RESPONSE; DRUG EFFECT; FEMALE; FRONTAL CORTEX; GESTATION PERIOD; LITTER SIZE; MALE; NEWBORN MORTALITY; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; RIGHTING REFLEX; SEX DIFFERENCE; STRAIN DIFFERENCE;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; BRAIN; FEMALE; MUSCULOSKELETAL EQUILIBRIUM; ORGAN SIZE; PREGNANCY; PREGNANCY OUTCOME; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SPECIES SPECIFICITY; TIME FACTORS; TRETINOIN;

EID: 0035018750     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0892-0362(01)00133-7     Document Type: Article

References (43)

1. Adams J. Ultrasonic vocalizations as diagnostic tools in studies of developmental toxicity: An investigation of the effects of hypervitaminosis A. Neurobehav. Toxicol. Teratol. 4:1982;299-304.
2. Altman J., McCrady B. The influence of nutrition on neural and behavioral development: IV. Effect of infantile undernutrition on the growth of the cerebellum. Dev. Psychobiol. 5:1972;111-122.
3. Barnes D., Altman J. Effects of different schedules of early undernutrition on the preweaning growth of the rat cerebellum. Exp. Neurol. 38:1973;406-419.
4. Batipps M., Miyaoka M., Shinohara M., Sokoloff L., Kennedy C. Comparative rates of local cerebral glucose utilization in the visual system of conscious albino and pigmented rats. Neurology. 31:1981;58-62.
5. Berquin P.C., Giedd J.N., Jacobsen L.K., Hamburger S.D., Krain A.L., Rapaport J.L., Castellanos F.X. Cerebellum in attention-deficit hyperactivity disorder: A morphometric MRI study. Neurology. 50:1998;1087-1093.
6. Chakraborty C., Chakraborty A.K., Chakraborty D.P. A comparative study of tryptophan metabolism in skins and livers of black and albino rats. Experientia. 40:1984;363.
7. Chan S.O., Baker G.E., Guillery R.W. Differential action of the albino mutation on two components of the rat's uncrossed retinofugal pathway. J. Comp. Neurol. 336:1993;362-377.
8. Chase H.P., Lindsley W.F.B., O'Brien D. Undernutrition and cerebellar development. Nature. 221:1969;554-555.
9. Ciesielski K.T., Harris R.J., Hart B.L., Pabst H.F. Cerebellar hypoplasia and frontal lobe cognitive deficits in disorders of early childhood. Neuropsychologia. 35:1997;643-655.
10. Creech Kraft J., Kochhar D.M., Scott W.J., Nau H. Low teratogenicity of 13-cis-retinoic acid (Isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis: Comparison to the all-trans-isomer. Toxicol. Appl. Pharmacol. 87:1987;474-482.
11. Creel D., Giolli R.A. Retinogeniculate projections in albino and ocularly hypopigmented rats. J. Comp. Neurol. 166:1976;445-456.
12. Desmond J.E., Gabrieli J.D.E., Wagner A.D., Ginier B.L., Glover G.H. Lobular patterns of cerebellar activation in verbal working-memory and finger-tapping tasks as revealed by functional MRI. J. Neurosci. 17:1997;9675-9685.
13. Dobbing J., Hopewell J.W., Lynch A. Vulnerability of developing brain: VII. Permanent deficit of neurons in cerebral and cerebellar cortex following early mild undernutrition. Exp. Neurol. 32:1971;439-447.
14. Edwards A.L. Experimental Design in Psychological Research. fourth ed. 1972;Holt, Rinehart and Winston, New York, NY.
15. Fish I., Winick M. Effect of malnutrition on regional growth of the developing rat brain. Exp. Neurol. 25:1969;534-540.
16. Griffin W.S.T., Woodward D.J., Chandra R. Malnutrition and brain development: Cerebellar weight, DNA, RNA, protein and histological correlations. J. Neurochem. 28:1977;1269-1279.
17. Guillery R.W., Sitthi Amorn C., Eighmy B.B. Mutants with abnormal visual pathways: An explanation of anomalous geniculate laminae. Science. 174:1971;831-832.
18. Henry J.P., Liu Y.-Y., Nadra W.E., Qian C.-G., Mormede P., LeMaire V., Ely D., Hendley E.D. Psychosocial stress can induce chronic hypertension in normotensive strains of rats. Hypertension. 21:1993;714-723.
19. Holson R.R. When is a rat a boy? Tassinari M.S. Organ System Maturation and Functional Postnatal Development. 1999;Teratology Society, Continuing Education Course.
20. Holson R.R., Adams J., Ferguson S.A. Gestational stage-specific effects of retinoic acid exposure in the rat. Neurotoxicol. Teratol. 21:1999;393-402.
21. Holson R.R., Adams J., Ferguson S.A., Scalzo F.M. Retinoic acid exposure on gestational days 11-13 impairs swallowing in rat offspring. Neurotoxicol. Teratol. 2000;. in press.
22. Holson R.R., Gazzara R.A., Ferguson S.A., Adams J. Behavioral effects of low-dose gestational day 11-13 retinoic acid exposure. Neurotoxicol. Teratol. 19:1997;355-362.
23. Holson R.R., Gazzara R.A., Ferguson S.A., Adams J. A behavioral and neuroanatomical investigation of the lethality caused by gestational day 11-13 retinoic acid exposure. Neurotoxicol. Teratol. 19:1997;347-353.
24. Holson R.R., Gazzara R.A., Ferguson S.A., Ali S.F., LaBorde J.B., Adams J. Gestational retinoic acid exposure: a sensitive period for effects on neonatal mortality and cerebellar development. Neurotoxicol. Teratol. 19:1997;335-346.
25. Jensh R.P., Kocchar D.M., Till M.K., Eskesen M.B. Effects of prenatal exposure to isotretinoin (13-cis retinoic acid) on neonatal vocalizations. Teratology. 43:1991;497.
26. Jueptner M., Weiller C. A review of differences between basal ganglia and cerebellar control of movements as revealed by functional imaging studies. Brain. 121:1998;1437-1449.
27. Kochhar D.M., Penner J.D., Satre M.A. Derivation of retinoic acid and metabolites from a teratogenic dose of retinol (vitamin A) in mice. Toxicol. Appl. Pharmacol. 96:1988;429-441.
28. Kruska D., Scott U. Vergleichend-quantitative untersuchungen an den Gehirn von Wander-und Laborratten: III. Volumenvergleich optischer Hirnzentren. J. Hirnförsch. 18:1977;59-67.
29. Lindsey J.R. Historical foundations. Baker H.J., Lindsey J.R., Weisbroth S.H. The Laboratory Rat: vol: 1. Biology and Diseases. 1979;1-36 Academic Press, New York.
30. Lockard R.B. The albino rat: A defensible choice or a bad habit? Am. Psychol. 23:1968;734-743.
31. Miller A.M., Chappell R., Obermeyer W.H., Benca R.M. Analysis of the retinohypothalamic tract in congenic albino and pigmented rats. Brain Res. 741:1996;348-351.
32. Milliken G.A. SAS tutorial: analysis of covariance - models, strategies and interpretations. Proceedings, 9th Annual SAS Users Group International Conference, Hollywood Beach, FL. 1984.
33. Mooney M.P., Hoyenga K.T., Hoyenga K.B., Morton J.C. Prenatal hypervitaminosis A and postnatal behavioral development in the rat. Neurobehav. Toxicol. Teratol. 3:1981;1-4.
34. Mostofsky S.H., Mazzocco M.M., Aakalu G., Warsofsky I.S., Denckla M.B., Reiss A.L. Decreased cerebellar posterior vermis size in fragile×syndrome: Correlation with neurocognitive performance. Neurology. 50:1998;121-130.
35. Neville H.W., Chase H.P. Undernutrition and cerebellar development. Exp. Neurol. 33:1971;485-497.
36. Nolen G.A. Variations in teratogenic response to hypervitaminosis A in three strains of the albino rat. Fd. Cosmet. Toxicol. 7:1969;209-214.
37. Ouchi Y., Okada H., Yoshikawa E., Nobezawa S., Futatsubashi M. Brain activation during maintenance of standing postures in humans. Brain. 122:1999;329-338.
38. Reiman E.M. The application of positron emission tomography to the study of normal and pathologic emotions. J. Clin. Psychiatry. 58(Suppl. 16):1997;4-12.
39. SAS/STAT Software: Changes and Enhancements Through Release 6.12: Chap. 10. The GENMOD Procedure. 1997;SAS Institute, Cary, NC.
40. Schmahmann J.D., Sherman J.C. The cerebellar cognitive affective syndrome. Brain. 121:1998;561-579.
41. Steininger T.L., Rye D.B., Gilliland M.A., Wainer B.H., Benca R.M. Differences in the retinohypothalamic tract in albino Lewis versus brown Norway rat strains. Neuroscience. 54:1993;11-14.
42. Wessel K., Nitschke M.F. Somatotopic representation and cerebro-cerebellar interconnections in ataxic patients. De Zeeuw C.I., Strata P., Voogd J. The Cerebellum: From Structure to Control. Prog. Brain Res. 114:1997;577-588.
43. Wise R.P., Lund R.D. The retina and central projections of heterochromic rats. Exp. Neurol. 51:1976;68-77.