Semicarbazide-sensitive amine oxidase catalyzes endothelial cell-mediated low density lipoprotein oxidation

Cardiovascular Research

Volumn 50, Issue 3, 2001, Pages 583-588

  Exner, Markus ^a   Hermann, Marcela ^a   Hofbauer, Roland ^a   Kapiotis, Stylianos ^a   Quehenberger, Peter ^a   Speiser, Wolfgang ^a   Held, Irmtraud ^a   Gmeiner, Bernhard M K ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Atherosclerosis; Endothelial function; Lipoproteins

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); APOPROTEIN; LOW DENSITY LIPOPROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ARTICLE; BINDING SITE; CATALYST; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; DEAMINATION; DIABETES MELLITUS; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME DENATURATION; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; LIPID OXIDATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN MODIFICATION; VASCULAR DISEASE;

AMINE OXIDASE (COPPER-CONTAINING); CATALYSIS; CELL CULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; HUMANS; LIPOPROTEINS, LDL; OXIDATION-REDUCTION;

EID: 0035018484     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00208-5     Document Type: Article

References (38)

1. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., Witztum J.L. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. New Engl. J. Med. 320:1989;915-924.
2. Steinberg D., Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis. Circulation. 95:1997;1062-1071.
3. Esterbauer H., Gebicki J., Puhl H., Jurgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic. Biol. Med. 13:1992;341-390.
4. Hazell L.J., Stocker R. Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages. Biochem. J. 290:1993;165-172.
5. Darley Usmar V.M., Hogg N., O'Leary V.J., Wilson M.T., Moncada S. The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. Free Radic. Res. Commun. 17:1992;9-20.
6. Chang G.J., Woo P., Honda H.M., Ignarro L.J., Young L., Berliner J.A., Demer L.L. Oxidation of LDL to a biologically active form by derivatives of nitric oxide and nitrite in the absence of superoxide. Dependence on pH and oxygen. Arterioscler. Thromb. 14:1994;1808-1814.
7. Wieland E., Parthasarathy S., Steinberg D. Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro: a model for in vivo oxidation? Proc. Natl. Acad. Sci. USA. 90:1993;5929-5933.
8. Bowry V.W., Ingold K.U., Stocker R. Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem. J. 288:1992;341-344.
9. Witting P.K., Upston J.M., Stocker R. Role of alpha-tocopheroxyl radical in the initiation of lipid peroxidation in human low-density lipoprotein exposed to horse radish peroxidase. Biochemistry. 36:1997;1251-1258.
10. Singh R.J., Feix J.B., Mchaourab H.S., Hogg N., Kalyanaraman B. Spin-labeling study of the oxidative damage to low-density lipoprotein. Arch. Biochem. Biophys. 320:1995;155-161.
11. Santanam N., Parthasarathy S. Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases. J. Clin. Invest. 95:1995;2594-2600.
12. Berliner J.A., Heinecke J.W. The role of oxidized lipoproteins in atherogenesis. Free Radic. Biol. Med. 20:1996;707-727.
13. Heinecke J.W., Baker L., Rosen H., Chait A. Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells. J. Clin. Invest. 77:1986;757-761.
14. Heinecke J.W., Rosen H., Chait A. Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture. J. Clin. Invest. 74:1984;1890-1894.
15. Smith C., Mitchinson M.J., Aruoma O.I., Halliwell B. Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions. Biochem. J. 286:1992;901-905.
16. Mukhopadhyay C.K., Ehrenwald E., Fox P.L. Ceruloplasmin enhances smooth muscle cell- and endothelial cell-mediated low density lipoprotein oxidation by a superoxide-dependent mechanism. J. Biol. Chem. 271:1996;14773-14778.
17. Ehrenwald E., Chisolm G.M., Fox P.L. Intact human ceruloplasmin oxidatively modifies low density lipoprotein. J. Biol. Chem. 93:1994;1493-1501.
18. Lamb D.J., Leake D.S. Acidic pH enables caeruloplasmin to catalyse the modification of low-density lipoprotein. FEBS Lett. 338:1994;122-126.
19. Fox P.L., Mukhopadhyay C., Ehrenwald E. Structure, oxidant activity, and cardiovascular mechanisms of human ceruloplasmin. Life Sci. 56:1995;1749-1758.
20. Mukhopadhyay C.K., Mazumder B., Lindley P.F., Fox P.L. Identification of the prooxidant site of human ceruloplasmin: a model for oxidative damage by copper bound to protein surfaces. Proc. Natl. Acad. Sci. USA. 94:1997;11546-11551.
21. Ehrenwald E., Fox P.L. Role of endogenous ceruloplasmin in low density lipoprotein oxidation by human U937 monocytic cells. J. Clin. Invest. 97:1996;884-890.
22. Yu P.H. Deamination of methylamine and angiopathy; toxicity of formaldehyde, oxidative stress and relevance to protein glycoxidation in diabetes. J. Neural. Transm. (Suppl.). 52:1998;201-216.
23. Deng Y., Boomsma F., Yu P.H. Deamination of methylamine and aminoacetone increases aldehydes and oxidative stress in rats. Life Sci. 63:1998;2049-2058.
24. Boomsma F., Derkx F.H., van den Meiracker A.H., Man in 't Veld A.J., Schalekamp M.A. Plasma semicarbazide-sensitive amine oxidase activity is elevated in diabetes mellitus and correlates with glycosylated haemoglobin. Clin. Sci. Colch. 88:1995;675-679.
25. Lizcano J.M., Tipton K.F., Unzeta M. Purification and characterization of membrane-bound semicarbazide-sensitive amine oxidase (SSAO) from bovine lung. Biochem. J. 331:1998;69-78.
26. Hermann M., Gmeiner B. Altered susceptibility to in vitro oxidation of LDL in LDL complexes and LDL aggregates. Arterioscler. Thromb. 12:1992;1503-1506.
27. Kapiotis S., Besemer J., Bevec D., Valent P., Bettelheim P., Lechner K., Speiser W. Interleukin-4 counteracts pyrogen-induced downregulation of thrombomodulin in cultured human vascular endothelial cells. Blood. 78:1991;410-415.
28. Steinbrecher U.P., Witztum J.L., Parthasarathy S., Steinberg D. Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism. Arteriosclerosis. 7:1987;135-143.
29. Okuyama T., Kobayashi Y. Determination of diamine oxidase activity by liquid scintillation counting. Arch. Biochem. Biophys. 95:1961;242-250.
30. Boomsma F., van Veldhuisen D.J., de Kam P.J., Man in 't Veld A.J., Mosterd A., Lie K.I., Schalekamp M.A. Plasma semicarbazide-sensitive amine oxidase is elevated in patients with congestive heart failure. Cardiovasc. Res. 33:1997;387-391.
31. Disilvestro R.A., Jones A.A., Smith D., Wildman R. Plasma diamine oxidase activities in renal dialysis patients, a human with spontaneous copper deficiency and marginally copper deficient rats. Clin. Biochem. 30:1997;559-563.
32. Yu P.H., Zuo D.M. Aminoguanidine inhibits semicarbazide-sensitive amine oxidase activity: implications for advanced glycation and diabetic complications. Diabetologia. 40:1997;1243-1250.
33. Kalant N., McCormick S. Inhibition by serum components of oxidation and collagen-binding of low-density lipoprotein. Biochim. Biophys. Acta. 1128:1992;211-219.
34. Dabbagh A.J., Frei B. Human suction blister interstitial fluid prevents metal ion-dependent oxidation of low density lipoprotein by macrophages and in cell-free systems. J. Clin. Invest. 96:1995;1958-1966.
35. Philis Tsimikas A., Parthasarathy S., Picard S., Palinski W., Witztum J.L. Aminoguanidine has both pro-oxidant and antioxidant activity toward LDL. Arterioscler. Thromb. Vasc. Biol. 15:1995;367-376.
36. Fox P.L., Mazumder B., Ehrenwald E., Mukhopadhyay C. Ceruloplasmin and cardiovascular disease. Free Radic. Biol. Med. 28:2000;1735-1744.
37. Kontush A., Meyer S., Finckh B., Kohlschütter A., Beisiegel U. alpha-Tocopherol as a reductant for Cu(II) in human lipoproteins. J. Biol. Chem. 271:1996;11106-11112.
38. Miyazaki H., Matsuoka H., Itabe H., Usui M., Ueda S., Okuda S., Imaizumi T. Hemodialysis impairs endothelial function via oxidative stress: effects of vitamin E-coated dialyzer. Circulation. 101:2000;1002-1006.