Identification and characterization of the genes for N-acetylglucosamine kinase and N-acetylglucosamine-phosphate deacetylase in the pathogenic fungus Candida albicans

European Journal of Biochemistry

Volumn 268, Issue 8, 2001, Pages 2498-2505

  Yamada Okabe, Toshiko ^a   Sakamori, Yoshimi ^a   Mio, Toshiyuki ^b   Yamada Okabe, Hisafumi ^a,b  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b NIPPON ROCHE RESEARCH CENTER   (Japan)

Author keywords

Candida albicans; N acetylglucosamine; N acetylglucosamine kinase; N acetylglucosamine phosphate deacetylase; Virulence

Indexed keywords

BACTERIAL ENZYME; FUNGAL ENZYME; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINE KINASE; N ACETYLGLUCOSAMINE PHOSPHATE DEACETYLASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; CELL GROWTH; CONTROLLED STUDY; ESCHERICHIA COLI; FUNGAL GENETICS; FUNGUS GROWTH; GENE DISRUPTION; GENE ISOLATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC CODE; GENOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; VIRULENCE;

AMIDOHYDROLASES; ANIMALS; CANDIDA ALBICANS; CARBON; ESCHERICHIA COLI; FUNGAL PROTEINS; GENE DELETION; GLUTATHIONE TRANSFERASE; MALE; MEMBRANE PROTEINS; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLASMIDS; POLYMERASE CHAIN REACTION; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY; TIME FACTORS;

BACTERIA (MICROORGANISMS); CANDIDA ALBICANS; ESCHERICHIA COLI; FUNGI; SACCHAROMYCES CEREVISIAE;

EID: 0035016306     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02135.x     Document Type: Article

References (24)

1. Glycoprotein biosynthesis in yeast
2. Synthesis of the yeast cell wall and its regulation
3. Cellular and molecular biology
4. Cloning of the glutamine: Fructose-6-phosphate amidotransferase gene from yeast: Pheromo-nal regulation of its transcription
5. Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucos-amine synthesis
6. Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase
7. The eukaryotic UDP-N-acetylglucosamine pyrophosphorylase: Gene cloning, protein expression, and catalytic mechanism
8. Induction of N-acetylglucosamine-catabolic pathway in spheroplasts of Candida albicans
9. Molecular cloning and analysis of the NAG1 cDNA coding for glucosamine-6-phosphate deaminase from Candida albicans
10. Molecular cloned mammalian glucosamine-6-phosphate deaminase localized to transporting epithelium and lacks oscillin activity
11. Sequence of the nagBACD operon in Escherichia coli K12 and pattern of transcription within the nag regulon
12. phospho-enolpyruvate-carbohydrate phosphotransferase systems of bacteria
13. Molecular cloning and characterization of murine and human N-acetylglucosamine kinase
14. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
15. Isogenic strain construction and gene mapping in Candida albicans
16. Transformation of intact yeast cells treated with alkali cations
17. Analysis of the nag regulon from Escherichia coli K12 and Klebsiella pneumoniae and of its regulation
18. Cloning and characterization of the N-acetylglucosamine operon of Escherichia coli
19. Current trends in Candida albicans research
20. The inducible N-acetylglucosamine catabolic pathway gene cluster in Candida albicans: Distinct N-acetylglucosamine-inducible factors interact at promoter of NAG1
21. N-Acetyl-d-glucosamine kinase and germ-tube formation in Candida albicans
22. Reduced virulence of Candida albicans mutants lacking the GNA1 gene encoding glucosamine-6-phosphate acetyltransferase