Human apolipoprotein A-IV metabolism within triglyceride-rich lipoproteins and plasma

Atherosclerosis

Volumn 156, Issue 2, 2001, Pages 363-372

  Sun, Zhiyong ^a   Lichtenstein, Alice H ^a   Dolnikowski, Gregory G ^a   Welty, Francine K ^a   Schaefer, Ernst J ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Aplipoprotein A IV; Apolipoprotein B48; Diet; Kinetics; Metabolism; Stable isotope; Tracer; Triglyceride rich lipoproteins

Indexed keywords

APOLIPOPROTEIN A4; APOLIPOPROTEIN B48; CHOLESTEROL; DEUTERIUM; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEUCINE; LIPOPROTEIN; RADIOACTIVE IODINE; STABLE ISOTOPE; TRACER; TRIGLYCERIDE RICH LIPOPROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CATABOLISM; COMPARTMENT MODEL; CONTROLLED STUDY; DIET RESTRICTION; DRUG INFUSION; FEEDING; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IMMUNOELECTROPHORESIS; IMMUNOPRECIPITATION; LIPOPROTEIN METABOLISM; MALE; NORMAL HUMAN; PLASMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TIME; ULTRACENTRIFUGATION;

ADULT; AGED; APOLIPOPROTEINS A; CORONARY ARTERIOSCLEROSIS; FEMALE; HUMANS; LIPOPROTEINS; MALE; MIDDLE AGED; RADIOIMMUNOASSAY; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TRIGLYCERIDES;

EID: 0035016016     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(00)00663-8     Document Type: Article

References (68)

1. Isolation and characterization of an apoprotein from the d less than 1.006 lipoproteins of human and canine lymph homologous with the rat A-IV apoprotein
2. Isolation and characterization of human apolipoprotein A-IV from lipoprotein-depleted serum
3. An apolipoprotein homolog of rat apolipoprotein A-IV in human plasma: Isolation and partial characterisation
4. Human intestinal lipoproteins: Studies in chyluric subjects
5. Apolipoprotein A-IV: A protein occurring in human mesenteric lymph chylomicrons and free in plasma: Isolation and quantification
6. Human apolipoprotein A-IV: Intestinal origin and distribution in plasma
7. Evidence for high density lipoproteins as the major apolipoprotein A-IV-containing fraction in normal human serum
8. Frequency and effect of human apolipoprotein A-IV polymorphism on lipid and lipoprotein levels in an Icelandic population
9. Genetic polymorphism of apolipoprotein A-IV in five different regions of Europe: Relations to plasma lipoproteins and to history of myocardial infarction: The EARS study. European Atherosclerosis Research Study
10. In vivo metabolism of apolipoprotein A-IV in severe hypertriglyceridemia: A combined radiotracer and stable isotope kinetic study
11. Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM
12. Sources of variability of human plasma apolipoprotein A-IV levels and relationships with lipid metabolism
13. Distribution of apolipoprotein A-IV in human plasma
14. Effect of lecithin-cholesterol acyltransferase on distribution of apolipoprotein A-IV among lipoproteins of human plasma
15. Plasma metabolism of apolipoprotein A-IV in humans
16. Metabolism of apolipoprotein A-IV
17. Studies on the in vivo and in vitro distribution of apolipoprotein A-IV in human plasma and lymph
18. Alterations in plasma levels of apolipoprotein A-IV in various clinical entities
19. Sensitivity of serum apolipoprotein A-IV levels to changes in dietary fat content
20. The response of apolipoprotein A-IV to cholesterol feeding in rats
21. Apolipoprotein A-IV synthesis in rat intestine: Regulation by dietary triglyceride
22. Transport of lipid and apolipoproteins A-I and A-IV in intestinal lymph of the rat
23. Increased apolipoprotein A-IV in rat mesenteric lymph after lipid meal acts as a physiological signal for satiation
24. Synthesis and lymphatic transport of intestinal apolipoprotein A-IV in response to graded doses of triglyceride
25. Postprandial lipaemia is associated with increased levels of apolipoprotein A-IV in the triacylglycerol-rich fraction and decreased levels in the denser plasma fractions
26. Activation of lecithin: Cholesterol acyltransferase by apolipoproteins E-2, E-3, and A-IV isolated from human plasma
27. Identification of specific amphipathic alpha-helical sequence of human apolipoprotein A-IV involved in lecithin: Cholesterol acyltransferase activation
28. Activation of lecithin: Cholesterol acyltransferase by human apolipoprotein A-IV
29. Activation of human plasma cholesterol ester transfer protein by human apolipoprotein A-IV
30. Distinctive structure and function of human apolipoprotein variant ApoA-IV-2
31. Human apolipoprotein A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol efflux from adipose cells
32. Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma
33. Protection against atherogenesis in mice mediated by human apolipoprotein A-IV
34. Apolipoprotein AIV: A potent endogenous inhibitor of lipid oxidation
35. Suppression of food intake by apolipoprotein A-IV is mediated through the central nervous system in rats
36. Effect of intravenous administration of apolipoprotein A-IV on patterns of feeding, drinking and ambulatory activity of rats
37. Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior
38. Mechanism of action of intracisternal apolipoprotein A-IV in inhibiting gastric acid secretion in rats
39. Apolipoprotein A-IV acts centrally in the brain to reduce the severity of gastric ulceration in the rat
40. Three genetic variants of human plasma apolipoprotein A-IV. apoA-IV-1 (Thr347 - Ser), apoA-IV-0(Lys167 - Glu, Gln360 - His), and apoA-IV-3(Glu165 - Lys)
41. The mutation causing the common apolipoprotein A-IV polymorphism is a glutamine to histidine substitution of amino acid 360
42. Human plasma apolipoproteins A-IV-0 and A-IV-3. Molecular basis for two rare variants of apolipoprotein A-IV-1
43. ApoA-IV phenotype affects diet-induced plasma LDL cholesterol lowering
44. Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele
45. Effect of 360His mutation in apolipoprotein A-IV on plasma HDL-cholesterol response to dietary fat
46. Effect of 347-serine mutation in apoprotein A-IV on plasma LDL cholesterol response to dietary fat
47. Association of the apolipoprotein A-IV codon 360 mutation in patients with Alzheimer's disease
48. Apolipoprotein A-IV polymorphism and its effect on plasma lipid and apolipoprotein concentrations
49. A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127
50. Molecular biology of apolipoprotein A-IV
51. DNA polymorphisms of human apolipoprotein A-IV gene: Frequency and effects on lipid, lipoprotein and apolipoprotein levels in a French population
52. No association of apolipoprotein A-IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics
53. Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B-100 and high density lipoprotein Apo A-1 production in human subjects using deuterated leucine: Effect of fasting and feeding
54. Ordovas Schaefer EJ. Measurement of human apolipoprotein B-48 and B-100 kinetics in triglyceriderich lipoproteins using [5, 5, 5-2H3] leucine
55. Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions
56. In vivo metabolism of apolipoproteins A-IV and A-I associated with high density lipoprotein in normolipidemic subjects
57. Rapid in vivo transport and catabolism of human apolipoprotein A-IV-1 and slower catabolism of the apoA-IV-2 isoprotein
58. Effects of age, gender, and lifestyle factors on plasma apolipoprotein A-IV concentrations
59. Chylomicron/chylomicron remnant turnover in humans: Evidence for margination of chylomicrons and poor conversion of larger to smaller chylomicron remnants
60. f 20-60) in moderate hypercholesterolemia: Relationships between apolipoprotein B kinetics and plasma lipoproteins
61. Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters
62. The redistribution and metabolism of iodinated apolipoprotein A-IV in rats
63. Protein synthesis in intestine mucosa: The effect of route of administration of precursor of amino acids
64. 14C- labeled essential amino acids given intragastric or intavenous infusion to rats on normal and protein free diets
65. 13C] leucine infused simultaneously by gut and vein
66. Correlation between apolipoprotein A-IV and triglyceride concentrations in human sera