Human trophoblast invasion and spiral artery transformation: The role of PECAM-1 in normal pregnancy, preeclampsia, and fetal growth restriction

American Journal of Pathology

Volumn 158, Issue 5, 2001, Pages 1713-1721

  Lyall, Fiona ^a   Bulmer, Judith Nicola ^b   Duffie, Elizabeth ^a   Cousins, Frances ^a   Theriault, Anne ^a   Robson, Stephen Courtenay ^b  

^a Medical Genetics   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CELL ADHESION; CELL TRANSFORMATION; CONTROLLED STUDY; CYTOTROPHOBLAST; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; INTRAUTERINE GROWTH RETARDATION; PATHOPHYSIOLOGY; PLACENTA; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL;

EID: 0035015364     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64127-2     Document Type: Article

References (58)

1. Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy
2. The physiological response of the vessels of the placental bed to normal pregnancy
3. Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy
4. The ultrastructure of the arterial supply of the human placenta in pregnancy complicated by fetal growth retardation
5. Ultrastructure of the spiral arteries in human placental bed at the end of normal pregnancy
6. Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants
7. Trophoblastic invasion and modification of uterine veins during placental development macaques
8. Pre-eclampsia: More than pregnancy-induced hypertension
9. A morphological and immunological study of human placental bed biopsies in miscarriage
10. Comparison of colour Doppler features and pathological findings in complicated early pregnancy
11. Histological study of the maternoembryonic interface in spontaneous abortion
12. Defective haemochorial placentation as a cause of miscarriage: A preliminary study
13. Placental changes in fetal growth retardation. Fetus and neonate
14. The relation of birth-weight to histological appearances in vessels of the placental bed
15. Placental bed spiral arteries in the hypertensive disorders of pregnancy
16. An ultrastructural study of utero placental arteries in hypertensive and normotensive pregnancy and fetal growth retardation
17. Defective extravillous trophoblast function and pre-eclampsia
18. The uteroplacental circulation: Extravillous trophoblast
19. Molecular and functional aspects of PECAM-1/CD31
20. Platelet-endothelial adhesion molecule (PECAM-1/CD31) and its alternatively spliced isoforms are expressed during early mammalian cardiovascular development
21. A human endothelial cell-restricted externally disposed plasmalemmal protein enriched in intercellular junctions
22. PECAM-1 is required for transendothelial migration of leukocytes
23. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
24. Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype
25. Human trophoblast invasion and spiral artery transformation: The role of nitric oxide
26. Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function
27. Measurement of human fetal growth
28. Normal values of pulsatility index from fetal vessels; a cross-sectional study of 1556 healthy fetuses
29. Selection biases invalidate current low birthweight-for-gestation standards
30. A refined and sensitive method for the quantitation of proteins utilizing the principle of protein-dye binding
31. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
32. The biology of PECAM-1
33. Expression of cell-adhesion molecules in placentae from pregnancies complicated by preeclampsia and intrauterine growth retardation
34. 92-kD type IV collagenase mediates invasion of human trophoblasts
35. Expression and possible function of the HLA-G chain in human cytotrophoblasts
36. Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGF-β3
37. Inhibition of TGFβ3 restores the invasive capability of extravillous trophoblasts in preeclamptic pregnancies
38. Cell adhesion molecules: Their role in pregnancy
39. Trophoblast differentiation during formation of anchoring in a model of the early human placenta in vitro
40. Distribution patterns of extracellular matrix components are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo
41. Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts
42. Human cytotrophoblast differentiation/invasion is abnormal in preeclampsia
43. Restoration of trophoblast invasion capability in preeclamptic villous explants by antisense knock-down of TGFβ3
44. An immunological study of endothelialization of uteroplacental vessels in human pregnancy - Evidence that the endothelium is focally disrupted by trophoblast in pre-eclampsia
45. The placental bed
46. Platelet endothelial cell adhesion molecule-1 is expressed by a subpopulation of human tropoblasts: A possible mechanism for trophoblast-endothelial interaction during haemochorial placentation
47. Normal expression of cell adhesion molecules in placentae from women with systemic lupus erythematosus
48. Interaction of interstitial trophoblast with placental bed capillaries and venules of normotensive and pre-eclamptic pregnancies
49. Expression of platelet-endothelial cell adhesion molecule-1 (PECAM) by macaque trophoblast cells during invasion of the spiral arteries
50. Comparison of uteroplacental blood flow in normal and intrauterine growth-retarded pregnancy
51. Spiral artery blood flow in the central and peripheral areas of the placental bed in the second trimester
52. Improved prediction of preeclampsia by two stage screening of uterine arteries using the early diastolic notch and color Doppler imaging
53. A high uterine artery pulsatility index reflects a defective development of placental bed spiral arteries in pregnancies complicated by hypertension and fetal growth retardation
54. Doppler flow measurements and histomorphology of the placental bed in uteroplacental insufficiency
55. A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies
56. Morphological changes in the utero-placental bed in pregnancy hypertension
57. Fetal growth retardation and the maternal arterial supply of the human placenta in the absence of sustained hypertension
58. Morphological changes of spiral arteries in the placental bed in relation to pre-eclampsia and fetal growth retardation