Effects of formulation variables and post-compression curing on drug release from a new sustained-release matrix material: Polyvinylacetate-povidone

Pharmaceutical Development and Technology

Volumn 6, Issue 2, 2001, Pages 247-254

  Shao, Z J ^a   Farooqi, M I ^a   Diaz, S ^a   Krishna, A K ^a   Muhammad, N A ^a  

^a PFIZER INC   (United States)

Author keywords

Diphenhydramine HCl; Kollidon SR; Matrix tablets; Polyvinylacetate; Sustained release

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; DIPHENHYDRAMINE; KOLLIDON SR; LACTOSE; POLYVINYL ACETATE; POVIDONE;

ARTICLE; DISSOLUTION; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; EXCIPIENT COMPATIBILITY; MATRIX TABLET; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; TABLET COMPRESSION; TABLET FORMULATION; TABLET MATRIX;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIPHENHYDRAMINE; POLYVINYLS; POVIDONE; SOLUBILITY; TABLETS;

EID: 0035014798     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100002201     Document Type: Article

References (25)

1. Effect of formulation variables on drug release from HPMC-based matrix tablets
2. Studies on drug release from a carbomer tablet matrix
3. Formulation and process variables affecting SCH 209149 release from ethylcellulose-based matrix tablets
4. Evaluation of the gum from hakea gibbosa as a sustained-release and mucoadhesive component in buccal tablets
5. Controlled release from spherical matrices prepared in a laboratory scale rotor-granulator-release mechanism interpretation using individual pellet data
6. Sustained release through coated microparticles of nifedipine
7. Preparation of agglomerated crystals for direct tabletting and microencapsulation by the spherical crystallization technique with a continuous system
8. Kollidon SR - A new excipient for sustained release matrices
9. Vinyl ester polymers
10. Mathematical modelling of drug release from hpmc matrices: Effect of temperature
11. Mechanisms of solute release from porous hydrophilic polymers
12. Defect diffusion model for volume and enthalpy recovery in amorphous polymers
13. Structural changes in glassy polymers
14. Processing considerations for an ec latex coating system: Influence of curing time and temperature
15. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices
16. Prediction of drug release from hydroxypropyl methylcellulose (HPMC) matrices: Effect of polymer concentration
17. Fundamental aspects of drug release from polymers. II. Approaches to governing kinetics of release
18. Studies on drug release kinetics from ibuprofen-carbomer hydrophilic matrix tablets: Influence of co-excipients on release rate of the drug
19. Poly(Ethylene oxide) (PEO) and different molecular weight PEO blends monolithic devices for drug release
20. Heparin release from hydrophobic polymers: (I). In vitro studies
21. Sustained-release oral delivery of theophylline by use of polyvinyl alcohol and polyvinyl alcohol-methyl acrylate polymers
22. Polymer blend matrix for oral sustained drug delivery
23. Sustained release of antimicrobial drugs from poly (vinyl alcohol) and gum arabica blend matrix