Use of a moist granulation technique (MGT) to develop controlled-release dosage forms of acetaminophen

Drug Development and Industrial Pharmacy

Volumn 27, Issue 4, 2001, Pages 337-343

  Railkar, Aniruddha M ^a   Schwartz, Joseph B ^b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

Agglomeration; Controlled release; Moist granulation technique

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; DILUENT; HYDROXYPROPYLCELLULOSE; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; PARACETAMOL; POVIDONE;

ARTICLE; CONTROLLED RELEASE FORMULATION; DRUG DOSAGE FORM; DRUG GRANULATION; PARTICLE SIZE; TABLET COMPRESSION;

ABSORPTION; ACETAMINOPHEN; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; PARTICLE SIZE; WATER;

EID: 0035014255     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100103733     Document Type: Article

References (5)

1. Moisture activated dry granulation: A general process
2. Log normal distribution of tablet pore diameter
3. Evaluating the flow properties of solids
4. Reducing dust and improving granule and tablet quality in the roller compaction process
5. Natural polymer hydrophilic matrix: Influencing drug release factors