Acute and chronic toxicity following parenteral application of erythromycin to maturing spring chinook salmon held at two water temperatures

Journal of Aquatic Animal Health

Volumn 13, Issue 1, 2001, Pages 8-19

  Moffitt, Christine M ^a   Kiryu, Yasunari ^b  

^a UNIVERSITY OF IDAHO   (United States)

^b VIRGINIA INSTITUTE OF MARINE SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONCORHYNCHUS TSHAWYTSCHA;

EID: 0035013252     PISSN: 08997659     EISSN: 15488667     Source Type: Journal    
DOI: 10.1577/1548-8667(2001)013<0008:AACTFP>2.0.CO;2     Document Type: Article

References (50)

1. Andersson, T., and U. Koivusaari. 1985. Influence of environmental temperature on the induction of xenobiotic metabolism by b-Naphthoflavone in rainbow trout, Salmo gairdneri. Toxicology and Applied Pharmacology 80:43–50.
2. Augusto, J., B. Smith, S. Smith, J. Robertson, and R. Reimschuessel. 1996. Gentamicin-induced nephrotoxicity and nephroneogenesis in Oreochromis nilotica, a tilapian fish. Diseases of Aquatic Organisms 26:49–58.
3. Barron, M. G., B. D. Tarr, and W. L. Hayton. 1987. Temperature dependence of Di-2-ethylhexyl Phthalate (DEHP) pharmacokinetics in rainbow trout. Toxicology and Applied Pharmacology 88:305–312.
4. Björklund, H., and G. Bylund. 1990. Temperaturerelated absorption and excretion of oxytetracycline in rainbow trout (Salmo gairdneri R.). Aquaculture 84:363–372.
5. Brett, J. R. 1995. Energetics pp 1–68 in C. Groot, L. Margolis, and W. C. Clarke, editors. Physiological ecology of Pacific salmon. University of British Columbia Press, Vancouver.
6. Cantor, A. B. 1997. Extending SAS survival analysis techniques for medical research. SAS Institute Inc., Cary, North Carolina.
7. Colgrove, G. S. 1966. Histological and hematological changes accompanying sexual maturation of sockeye salmon in the Fraser River system. International Pacific Salmon Fisheries Commission, Bulletin XX. New Westminster, B.C., Canada.
8. Cotran, R. S., V. Kumar, and T. Collins, editors. 1999. Robbins pathologic basis of disease, 6th edition. W. B. Saunders Company, Philadelphia.
9. Elliott, D. G., R. J. Pascho, and G. L. Bullock. 1989. Developments in the control of bacterial kidney disease of salmonid fishes. Diseases of Aquatic Organisms 6:201–215.
10. Endo, M., T. Sakai, T. Yamaguchi, and H. Nakajima. 1992. Pathology of jaundice in the cultured eel Anguilla japonica. Aquaculture 103:1–7.
11. Evelyn, T. P. T., J. E. Ketcheson, and L. Prosperi-Porta. 1986. Use of erythromycin as a means of preventing vertical transmission of Renibacterium salmoninarum. Diseases of Aquatic Organisms 2:7–11.
12. Everall, N. C., C. G. Mitchell, D. B. Groman, and J. A. A. Johnston. 1991. Tracing of haematotoxic agents in water with the aid of captive fish: a study with captive adult Atlantic salmon Salmo salar in the River Don, Aberdeenshire, Scotland. Diseases of Aquatic Organisms 10:75–85.
13. Everall, N. C., C. G. Mitchell, and J. N. Robson. 1992. Effluent causes of the “pigmented salmon syndrome” in wild adult Atlantic salmon Salmo salar from the River Don in Aberdeenshire. Diseases of Aquatic Organisms 12:199–205.
14. Fö rlin, L. 1980. Effects of clophen A50, 3-methylcholanthrene, pregnenolone-16-carbonitrile, and phenobarbital on the hepatic microsomal cytochrome P-450-dependent monooxygenase system in rainbow trout, Salmo gairdneri, of different age and sex. Toxicology and Applied Pharmacology 54:420–430.
15. Gilman, A. G., T. W. Rall, A. S. Nies, and P. Taylor, editors. 1990. Goodman and Gilman’s the pharmacological basis of therapeutics, 8th edition. McGraw-Hill, Inc., New York.
16. Goksøyr, A., and H. E. Larsen. 1991. The cytochrome P450 system of Atlantic salmon (Salmo salar): I. Basal properties and induction of P450 1A1 in liver of immature and mature fish. Fish Physiology and Biochemistry 9:339–349.
17. Groman, D. B., and G. W. Klontz. 1983. Chemotherapy and prophylaxis of bacterial kidney disease with erythromycin. Journal of the World Mariculture Society 14:226–235.
18. Groman, D. B., and K. Miller. 1987. Haemolytic anaemia of wild Atlantic salmon: haematology and chemical pathology. Aquaculture 67:210–212.
19. Hansson, T., J. Rafter, and J-A°. Gustafsson. 1979. Effects of some common inducers on the hepatic microsomal metabolism of androstenedione in rainbow trout with special reference to cytochrome P-450-dependent enzymes. Biochemical Pharmacology 29:583–587.
20. Haukenes, A. H. 1995. Characterization of erythromycin depletion in the tissues and plasma of adult chinook salmon (Oncorhynchus tshawytscha) following injection. Master’s thesis., University of Idaho, Moscow, Idaho.
21. Haukenes, A. H., and C. M. Moffitt. 1999. Concentrations of erythromycin in maturing chinook salmon after intraperitoneal injection of one of two drug formulations. Journal of Aquatic Animal Heath 11: 61–67.
22. Hicks, B. D., and J. R. Geraci. 1984. A histological assessment of damage in rainbow trout, Salmo gairdneri Richardson, fed rations containing erythromycin. Journal of Fish Diseases 7:457–465.
23. Jimenez, B. D., and J. J. Stegeman. 1990. Detoxication enzymes as indicators of environmental stress on fish. American Fisheries Society Symposium 8:67–79.
24. Jubb, K. V. F., P. C. Kennedy, and N. Palmer. 1993. Pathology of Domestic Animals, 4th edition, volume 3. Academic Press, San Diego, California.
25. Kawatsu, H., and T. Sakai. 1980. Hyperbilirubinemia in cultured eel. Bulletin of the Japanese Society of Scientific Fisheries 46:809–812.
26. Klontz, G. W. 1983. Bacterial kidney disease in salmonids: an overview. Pages 177–200 in D. P. Anderson, M. Dorson, and P. H. Dubourget, editors. International symposium on the antigens of fish pathogens: development and productions for vaccines and serodiagnostics. Collection Fondation Marcel Merieux, Lyon, France.
27. Kucers, A. 1972. Erythromycin. Pages 207–221 in W. Heinemann, editor. The use of antibiotics, 3rd edition. Medical Books, Ltd., London.
28. Larsen, H. E., M. Celander, and A. Goksøyr. 1992. The cytochrome P450 system of Atlantic salmon (Salmo salar): II. Variations in hepatic catalytic activities and isozyme patterns during an annual reproductive cycle. Fish Physiology and Biochemistry 10:291–301.
29. Law, F. C. P. 1999. A physiologically based pharmacokinetic model for predicting the withdrawal period of oxytetracycline in cultured chinook salmon, Oncorhynchus tshawytscha, pp 105–122 in S. J. Smith, W. H. Gingerich, and M. G. Beconi-Barker editors. Xenobiotics in Fish. Kluwer Academic/Plenum Publishers, New York.
30. Lee, E. T. 1992. Statistical methods for survival analysis, 2nd edition. John Wiley and Sons, Inc., New York.
31. Luna, L. G., editor. 1968. Manual of histologic staining methods of the Armed Forces Institute of Pathology, 3rd edition. McGraw-Hill Book Company, New York.
32. Marking, L. L., G. E. Howe, and J. R. Crowther. 1988. Toxicity of erythromycin, oxytetracycline, and tetracycline administered to lake trout in water baths, by injection, or by feeding. Progressive Fish-Culturist 50: 197–201.
33. Mayer, F. L., Jr., L. L. Marking, L. E. Pedigo, J. A. Brecken. 1989. Physiochemical factors affecting toxicity: pH, salinity and temperature Part I. Literature Review. Environmental Research Laboratory, U.S. Environmental Protection Agency, Gulf Breeze, Florida.
34. Moffitt, C. M. 1998. Field trials of investigational new animal drugs. Veterinary and Human Toxicology 40:48–52.
35. Moffitt, C. M., and Y. Kiryu. 1999. Toxicity, teratogenesis, and efficacy of injectable erythromycin (Erythro-200) administered repeatedly to adult spring chinook salmon. Journal of Aquatic Animal Heath 11:1–9.
36. Moffitt, C. M., and J. A. Schreck. 1988. Accumulation and depletion of orally administered erythromycin thiocyanate in tissues of chinook salmon. Transactions of the American Fisheries Society 117:394–400
37. Pascho, R. J., D. G. Elliott, and J. M. Streufert. 1991. Brood stock segregation of spring chinook salmon Oncorhynchus tshawytscha by use of the enzymelinked immunosorbent assay (ELISA) and the fluorescent antibody technique (FAT) affects the prevalence and levels of Renibacterium salmoninarum infection in progeny. Diseases of Aquatic Organisms 12:25–40.
38. Piper, R. G. 1961. Toxic effects of erythromycin thiocyanate on rainbow trout. Progressive Fish-Culturist 23:134–135.
39. Robertson, O. H., and B. C. Wexler. 1960. Histological changes in the organs and tissues of migrating and spawning pacific salmon (genus Oncorhynchus). Endocrinology 66:222–239.
40. Robertson, O. H., and B. C. Wexler. 1962. Histological changes in the organs and tissues of senile castrated kokanee salmon (Oncorhynchus nerka kennerlyi). General and Comparative Endocrinology 2:458–472.
41. SAS Institute. 1989. SAS/STAT user’s guide, version 6, 4th edition. SAS Institute Inc., Cary, North Carolina.
42. Slauson, D. O., and B. J. Cooper. 1990. Mechanisms of disease: a textbook of comparative general pathology, 2nd edition. Williams and Wilkins, Baltimore, Maryland. Sorimachi, M., Y.
43. Maeno, K. Nakajima, K. Inouye, and Y. Inui. 1993. Causative agent of jaundice of yellowtail, Seriola quinqueradiata (in Japanese). Gyobyo Kenkyu 28:119–124.
44. Stegeman, J. J. 1979. Temperature influence on basal activity and induction of mixed function oxygenase activity in Fundulus heteroclitus. Journal of the Fisheries Research Board of Canada 36:1400–1405.
45. Thomson, R. G. 1984. General Veterinary Pathology, 2nd edition. Saunders Company, Philadelphia
46. Wada, S., K. Hatai, and S. S. Kubota. 1989. Light microscopical observations of cultured yellowtail Seriola quinqueradiata, characterized by yellow discoloration of body surface (in Japanese). Gyobyo Kenkyu 24:211–218.
47. Warren J. W. 1963. Toxicity tests of erythromycin thiocyanate in rainbow trout. Progressive Fish-Culturist 25:88–92.
48. Webb, P. W. 1993. Swimming. Chapter 2 in D. H. Evans, editor. The Physiology of Fishes. CRC Press, Boca Raton, Florida.
49. Williams, D. E., B. S. S. Masters, J. J. Lech, and D. R. Buhler. 1986. Sex differences in cytochrome P-450 isozyme composition and activity in kidney microsomes of mature rainbow trout. Biochemical Pharmacology 35:2017–2023.
50. Yasutake, W. T., and J. H. Wales. 1983. Microscopic anatomy of salmonids: an atlas. U.S. Department of the Interior Fish and Wildlife Service, Resource Publication 150, Washington, D.C.