Phosphorylation of purified recombinant hepatitis B virus-X protein by mitogen-activated protein kinase and protein kinase C in vitro

Journal of Virological Methods

Volumn 95, Issue 1-2, 2001, Pages 1-10

  Lee, Young I ^a,b   Kim, Sun O ^a   Kwon, Hyok J ^a   Park, Jong G ^b   Sohn, Mi J ^a   Jeong, Soon S ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Dongsan Medical Center   (South Korea)

Author keywords

Circular dichroism; Hepatitis B virus X protein; Mitogen activated protein kinase; Protein kinase C

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOAMINO ACID; PROTEIN KINASE; PROTEIN KINASE C; RECOMBINANT PROTEIN; SERINE; UREA; VIRUS PROTEIN;

ARTICLE; CELL INCLUSION; CIRCULAR DICHROISM; ENZYME ACTIVITY; ESCHERICHIA COLI; FLUORESCENCE; HEPATITIS B VIRUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN RENATURATION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; HEPATITIS B VIRUS; HUMANS; HYDROLYSIS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; PHOSPHOAMINO ACIDS; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN RENATURATION; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS, PROTEIN; TRANS-ACTIVATORS;

ADENOVIRIDAE; ESCHERICHIA COLI; HEPATITIS B VIRUS;

EID: 0035013093     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-0934(00)00282-2     Document Type: Article

References (23)

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2. Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signalling cascade
3. Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus-X protein and may play a role in X-transactivation
4. The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II
5. The X protein of hepatitis B virus has a ribo/deoxy ATPase activity
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