Efficacy of urokinase and alteplase to reopen occluded central venous catheters in children

Journal of Pharmacy Technology

Volumn 17, Issue 3, 2001, Pages 95-98

  Bussières, Jean François ^a,c   Therrien, Roxane ^a   David, Michèle ^a   Leclair, Jean Pierre ^a   Harel, François ^b  

^a UNIVERSITY OF MONTREAL   (Canada)

^b MONTREAL HEART INSTITUTE   (Canada)

^c Montréal Heart Institute ^*  (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; UROKINASE;

ADOLESCENT; ARTICLE; BLOOD CLOT LYSIS; CENTRAL VENOUS CATHETER; CHILD; CONTROLLED STUDY; DRUG EFFICACY; DRUG INDICATION; DRUG SAFETY; FEMALE; FIBRIN DEPOSITION; HUMAN; MAJOR CLINICAL STUDY; MALE;

EID: 0035012729     PISSN: 87551225     EISSN: None     Source Type: Journal    
DOI: 10.1177/875512250101700304     Document Type: Article

References (23)

1. Suhocki PV, Conlon PJ Jr, Knelson MH, Harland R, Schwab SJ. Silastic cuffed catheters for hemodialysis vascular access: thrombolytic and mechanical correction of malfunction. Am J Kidney Dis 1996;28:379-86.
2. Hurtubise MR, Bottino JC, Lawson M, McCredie KB. Restoring patency of occluded central venous catheters. Arch Surg 1980; 115:212-3.
3. Andrew M, Michelson AD, Bovill E, Leaker M, Massicotte MP. Guidelines for antithrombotic therapy in pediatric patients. J Pediatr 1998;132:575-88.
4. Food and Drug Administration. Center for Biologics Evaluation and Research. Department of Health and Human Services. Warning letter. Update Abbokinase (urokinase). March 16, 1999.
5. Weitz JI, Stewart RJ, Fredenburgh JC. Mechanism of action of plasminogen activators. Thromb Haemost 1999;82:974-82.
6. Atkinson JB, Bagnall HA, Gomperts E. Investigational use of tissue plasminogen activator (t-PA) for occluded central venous catheters. J Parenteral Enteral Nutr 1990;14:310-1.
7. Paulsen D, Reisaether A, Aasen M, Fauchald P. Use of tissue plasminogen activator for reopening of clotted dialysis catheters. Nephron 1993;64-468-70.
8. Haire WD, Atkinson JB, Stephens LC, Kotulak GD. Urokinase versus recombinant plasminogen activator in thrombosed central venous catheters: a double-blinded, randomized trial. Thrombos Haemostas 1994;72:543-7.
9. Kleta R, Schleef J, Jürgens H. Tissue plasminogen activator and obstructed central venous catheters (letter). Med Pediatr Oncol 1998;30:376.
10. Canadian Pharmacists Association. Compendium des produits et specialites pharmaceutiques. 36th ed. Ottawa, Ontario, 2001.
11. Ward C, Weck S. Dilution and storage of recombinant tissue plasminogen activator (Activase) in balanced salt solutions. Am J Ophthalmol 1990;109:98-9.
12. Jaffe GJ, Green GDJ, Abrams GW. Stability of recombinant tissue plasminogen activator. Am J Ophthalmol 1989;108:90-1.
13. Breslow NE, Day NE. Statistical methods in cancer research. Volume 1: the analysis of case-control studies. Lyon, France: International Agency for Research on Cancer, 1980.
14. Glynn MFX, Phil D, Path MRC, Langer B, Jeejeebhoy KN. Therapy for thrombotic occlusion of long-term intravenous alimentation catheters. J Parenteral Enteral Nutr 1980;4:387-90.
15. Lawson M, Bottino JC, Hurtubise MR, McCredie KB. The use of urokinase to restore the patency of occluded central venous catheters. Am J IV Clin Nutr 1982;(Oct):29-32.
16. Winthrop AL, Wesson DE. Urokinase in the treatment of occluded central venous catheters in children. J Pediatr Surg 1984;19:536-8.
17. Wachs T. Urokinase administration in pediatric patients with occluded central venous catheters. J IV Nurs 1990;13:100-2.
18. Gale GB, O'Connor DM, Chu JY, Stanley D. Restoring patency of thrombosed catheters with cryopreserved urokinase. J Parenteral Enteral Nutr 1984;8:298-9.
19. Schneider TC, Krzywda E, Andris D, Quebbeman EJ. The malfunctioning silastic catheter - radiologic assessment and treatment. J Parenteral Enteral Nutr 1986;10:70-3.
20. Kellam B, Fraze D, Kanarek KS. Clot lysis for thrombosed central venous catheters in pediatric patients. J Perinatol 1987;7:242-4.
21. Northsea C. Using urokinase to restore patency in double lumen catheters. ANNA J 1994;21:261-73.
22. Rubie H, Juricic M, Claeyssens S, Krimou A, Lemozy J, Izard P, et al. Morbidity using subcutaneous ports and efficacy of vancomycin flushing in cancer. Arch Dis Child 1995;72:325-9.
23. Monturo CA, Dickerson RN, Mullen JL. Efficacy of thrombolytic therapy for occlusion of long-term catheters. J Parenteral Enteral Nutr 1990;14:312-4.