Testing for detailed balance (microscopic reversibility) in ion channel gating

Biophysical Journal

Volumn 80, Issue 6, 2001, Pages 3025-3026

  Rothberg, Brad S ^a   Magleby, Karl L ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION; ION CHANNEL;

ANALYTIC METHOD; CHANNEL GATING; ION TRANSPORT; LETTER; MICROSCOPY;

EID: 0035010215     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76268-6     Document Type: Letter

References (15)

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3. The principles of the stochastic interpretation of ion-channel mechanisms
4. A note on correlation in single ion channel records
5. Identification of aggregated Markovian models: Application to the nicotinic acetylcholine receptor
6. Glutamate receptor channel kinetics: The effect of glutamate concentration
7. Kinetic time constants independent of previous single-channel activity suggest Markov gating for a large conductance Ca-activated K channel
8. Two-dimensional components and hidden dependencies provide insight into ion channel gating mechanisms
9. Investigating single-channel gating mechanisms through analysis of two-dimensional dwell-time distributions
10. + channels using two-dimensional dwell-time distributions
11. On the time reversal of noise signals
12. Frequencies of paired open-closed durations of ion channels. Method of evaluation from single-channel recordings
13. Relationship between statistical properties of single ionic channel recordings and the thermodynamic state of the channels
14. Steady-state coupling of ion-channel conformations to a transmembrane ion gradient
15. The effects of non-identifiability on testing for detailed balance in aggregated markov models for ion-channel gating