Identifying chromosomal fragile sites from a hierarchical-clustering point of view

Biometrics

Volumn 57, Issue 2, 2001, Pages 435-440

  Hou, Chia Ding ^a   Chiang, Jengtung ^b   Tai, John Jen ^c  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b NATIONAL CHENGCHI UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Equiprobability model; Fragile site; Hierarchical clustering; Multiple hypothesis testing; Proportional probability model

Indexed keywords

STATISTICAL TESTS;

BREAKPOINT; CARCINOGENESES; EQUIPROBABILITY MODEL; FRAGILE SITE; GENETIC ABNORMALITY; HIER-ARCHICAL CLUSTERING; HIERARCHICAL CLUSTERING; MULTIPLE HYPOTHESES TESTING; PROBABILITY MODELLING; PROPORTIONAL PROBABILITY MODEL;

CHROMOSOMES;

ARTICLE; CARCINOGENESIS; CHROMOSOME ABERRATION; CHROMOSOME FRAGILITY; CLINICAL ARTICLE; CLUSTER ANALYSIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MATHEMATICAL ANALYSIS; PROBABILITY;

EID: 0035009458     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0006-341X.2001.00435.x     Document Type: Article

References (24)

1. Bohm, U., Dahin, P. F., McAllister, B. F., and Greenbaum, I. F. (1995). Identifying chromosomal fragile sites from individuals: A multinomial statistical model. Human Genetics 95, 249-256.
2. Chen, C.-H., Shih, H.-H., Wang-Wuu, S., Tai, J. J., and Wuu, K.-D. (1998). Chromosomal fragile site expression in lymphocytes from patients with schizophrenia. Human Genetics 103, 702-706.
3. De Braekeleer, M. and Smith, B. (1988). Two methods for measuring the non-randomness of chromosome abnormalities. Annals of Human Genetics 52, 63-67.
4. Hair, J. F., Jr., Anderson, R. E., Tatham, R. L., and Black, W. C. (1998). Multivariate Data Analysis. London: Prentice-Hall.
5. Hecht, F. and Sutherland, G. R. (1984). Fragile sites and cancer breakpoints. Cancer Genetics and Cytogenetics 12, 179-181.
6. Hochberg, Y. (1988). A sharper Bonferroni procedure for multiple tests of significance. Biometrika 75, 800-802.
7. Holm, S. (1979). A simple sequentially rejective multiple test procedure. Scandinavian Journal of Statistics 6, 65-70.
8. HOU, C.-D., Chiang. J., and Tai, J. J. (1999). Testing the nonrandomness of chromosomal breakpoints using highest observed breakage. Human Genetics 104, 350-355.
9. ISCN. (1981). An international system for human cytogenetic nomenclature - High resolution banding. Cytogenetics and Cell Genetics 31, 1-23.
10. Johnson, R. A. and Wiehern, D. W. (1998). Applied Multivariate Statistical Analysis. London: Prentice-Hall.
11. Koehler, K. and Larntz, K. (1980). An empirical investigation of goodness-of-fit statistics for sparse multinomials. Journal of the American Statistical Association 75, 336-344.
12. Le Beau, M. M. (1986). Chromosomal fragile sites and cancer-specific rearrangements. Blood 67, 849-858.
13. Mariani, T. (1989). Fragile sites and statistics. Human Genetics 81, 319-322.
14. Ried, K., Finnis, M., Hobson, L., et al. (2000). Common chromosomal fragile site FRA16D sequence: Identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells. Human Molecular Genetics 9, 1051-1663.
15. Seber, G. A. (1977). Linear Regression Analysis. New York: Wiley.
16. Smith, C. A. B. (1986). Chi-squared tests with small numbers. Annals of Human Genetics 50, 163-167.
17. Sozzi, G., Veronese, M. L., Negrini, M., et al. (1996). The FIHT gene at 3p14.2 is abnormal in lung cancer. Cell 85, 17-26.
18. Sutherland, G. R. and Hecht, F. (1985). Fragile Sites on Human Chromosomes. Oxford: Oxford University Press.
19. Sutherland, G. R. and Ledbetter, D. H. (1989). Report of the committee on cytogenetic markers. Tenth International Workshop on Human Gene Mapping. Cytogenctics and Cell Genetics 51, 452-458.
20. Tai, J. J. and Hou, C.-D. (1999). Methodological development in analysis of cytogenetic data. Journal of Genetics and Molecular Biology 10, 113-118.
21. Tai, J., J., Hou, C.-D., Wang-Wuu, S., Wang, C.-H., Leu, S.-Y., and Wuu, K.-D. (1993). A method for testing the nonrandomness of chromosomal breakpoints. Cytogenetics and Cell Genetics 63, 147-150.
22. Tai, J. J., Hou, C-D., and Wang-Wuu, S. (1998). A confirmation analysis method for identification of chromosomal fragile sites. Cancer Genetics and Cytogenetics 105, 1-5.
23. Troendle, J. F. (1995). A stepwise resampling method of multiple hypothesis testing. Journal of the American Statistical Association 90, 370-378.
24. Wang, C.-H. (1992). Chromosomal fragile sites expression in lymphocytes of patients with colorectal carcinoma and of healthy controls. MS thesis, National Yang-Ming University, Taipei, Taiwan.