Chemorepellent signaling through the PACAP/lysozyme receptor is mediated through cAMP and PKC in Tetrahymena thermophila

Journal of Comparative Physiology - A Sensory, Neural, and Behavioral Physiology

Volumn 187, Issue 3, 2001, Pages 171-176

  Hassenzahl, D L ^a   Yorgey, N K ^a   Keedy, M D ^a   Price, A R ^a,b   Hall, J A ^a,b   Myzcka, C C ^a,b   Kuruvilla, H G ^a,b  

^a CEDARVILLE UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

Chemorepellent; G protein; PACAP 38; PKC; Tetrahymena

Indexed keywords

CYCLIC AMP; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; LYSOZYME; NEUROPEPTIDE; PROTEIN KINASE C;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; CHEMORECEPTOR; LOCOMOTION; PHYSIOLOGY; TETRAHYMENA THERMOPHILA;

ANIMALS; BEHAVIOR, ANIMAL; CHEMORECEPTORS; CYCLIC AMP; LOCOMOTION; MURAMIDASE; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROTEIN KINASE C; TETRAHYMENA THERMOPHILA;

ANIMALIA; TETRAHYMENA; TETRAHYMENA THERMOPHILA;

EID: 0035008888     PISSN: 03407594     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003590100185     Document Type: Article

References (29)

1. Alam S, Banno Y, Nozawa Y (1993) Purification and characterization of phospholipase C preferentially hydrolyzing phosphatidylcholine in Tetrahymena membranes. J Eukaryot Microbiol 40:775-781
2. Basille M, Gonzalez BJ, Desrues L, Demas M, Fournier A, Vaudry H (1995) Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates adenylyl cyclase and phospholipase C activity in rat cerebellar neuroblasts. J Neurochem 65:1318-1324
3. Birkenbeil H (2000) Pharmacological study of signal transduction during stimulation of prothoracic glands from Manduca sexta. J Insect Physiol 46:1409-1414
4. Chu Z, Hablitz JJ (2000) Quisquilate induces an inward current via mGluR activation in neocortical pyramidal neurons. Brain Res 879:88-92
5. Colamarino SA, Tessier-Lavigne M (1995) The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear neurons. Cell 81:621-629
6. Delporte C, Poloczek P, Neef P de, Vertongen P, Ciccarelli E, Svoboda M, Herchuelz A, Winand J, Robberecht P (1995) Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide stimulate two signaling pathways in CHO cells stably transfected with the selective type PACAP receptor. Mol Cell Endocrinol 107:71-76
7. Dentier WL (1988) Fractionation of Tetrahymena ciliary membranes with Triton X-114 and the identification of a ciliary membrane ATPase. J Cell Biol 107:2679-2688
8. Francis JT, Hennessey TM (1995) Chemorepellents in Paramecium and Tetrahymena. J Eukaryot Microbiol 42:78-83
9. Gallagher HC, Odumeru OA, Regan CM (2000) Regulation of neural cell adhesion model polysialylation state by cell-cell contact and protein kinase C delta. J Neurosci Res 61:636-645
10. Hahm SH, Hsu C, Eiden LE (1998) PACAP activates calcium influx-dependent and -independent pathways to couple metenkephalin secretion and biosynthesis in chromaffin cells. J Mol Neurosci 11:43-56
11. Hegyesi H, Csaba G (1994) A calcium-dependent protein kinase is present in Tetrahymena. Cell Biochem Funct 12:221-226
12. Hennessey TM, Kim MY, Satir BH (1995) Lysozyme acts as a chemorepellent and secretagogue in Paramecium by activating a novel receptor-operated Ca conductance. J Membr Biol 98:145-155
13. Kalda A, Kaasik A, Vassiljev V, Pokk P, Zharkovsky A (2000) Neuroprotective action of group I metabotropic glutamate receptor agonists against oxygen-glucose deprivation-induced neuronal death. Brain Res 853:370-373
14. Kovacs P, Csaba G, Nakashima S, Nozawa Y (1997) Phospholipase D activity in the Tetrahymena pyriformis GL. Cell Biochem Funct 15:53-60
15. Kuruvilla HG, Hennessey TM (1998) Purification and characterization of a novel chemorepellent receptor from Tetrahymena thermophila. J Membr Biol 162:51-57
16. Kuruvilla HG, Kim MY, Hennessey TM (1997) Chemosensory adaptation to lysozyme and GTP involves independently regulated receptors in Tetrahymena thermophila. J Eukaryot Microbiol 44:263-268
17. Liu GJ, Madsen BW (1998) Modulatory action of PACAP27 on NMDA receptor channel activity in cultured chick cortical neurons. Brain Res 791:290-294
18. Mace SR, Dean JG, Murphy JR, Rhodes JL, Kuruvilla HG (2000) PACAP-38 is a chemorepellent and agonist for the lysozyme receptor in Tetrahymena thermophila. J Comp Physiol A 186:39-43
19. Messersmith EK, Leonardo ED, Shatz CJ, Tessier-Lavigne M, Goodman CS, Kolodkin AL (1995) Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14:949-959
20. Miyata A, Arimura A, Dahl RR, Minamino N, Uehara A, Jiang L, Culler MD, Coy DH (1989) Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells. Biochem Biophys Res Commun 164:567-574
21. Parent CA, Devreotes PN (1999) A cell's sense of direction. Science 284:765-770
22. Pang PKT, Kline LW (1997) Protein kinase C mediates the contractile action of pituitary adenylate cyclase activating polypeptide in guinea pig gallbladder strips. Regul Pept 77:63-67
23. Pang PKT, Kline LW (1998) Protein kinase C mediates the contractile actions of pituitary adenylate cyclase activating polypeptide in guinea pig gallbladder strips. Regul Peptides 77:63-67
24. Poznansky MC, Olszak IT, Foxall R, Evans RH, Luster AD, Scadden DT (2000) Active movement of T cells away from a chemokine. Nat Med 6:543-548
25. Straarup EM, Schousboe P, Hansen HQ, Kristiansen K, Hoffman EK, Rasmussen L, Christensen ST (1997) Effects of protein kinase C activators and staurosporine on protein kinase activity, cell survival, and proliferation in Tetrahymena thermophila. Microbios 91:181-190
26. Sweet MT, Carlson G, Cook RG, Nelson D, Allis CD (1997) Phosphorylation of linker histones by a protein kinase A-like activity in mitotic nuclei. J Biol Chem 272:916-923
27. 2+ release from ryanodine/caffeine stores through a novel pathway independent of both inositol trisphosphates and cyclic AMP in bovine adrenal medullary cells. J Neurochem 70:1652-1661
28. Vaudry D, Basille M, Anouar Y, Fournier A, Vaudry H, Gonzalez BJ (1998) The neurotrophic activity of PACAP on rat cerebellar granule cells is associated with activation of the protein kinase A pathway and c-fos gene expression. Ann NY Acad Sci 865:92-99
29. Zlotnik A, Yoshie O (2000) Chemokines: a new classification system and their role in immunity. Immunity 12:121-127