A rare etiology of hepatic steatosis associated with lactic acidosis: The toxicity of antiviral nucleoside analogues;Une étiologie rare de stéatose hépatique avec acidose lactique: La toxicité des analogues nucléosidiques anti-viraux

Annales de Pathologie

Volumn 21, Issue 2, 2001, Pages 160-163

  Bienvenu, Laurent ^a   Burel, Fanny ^b   Hofman, Véronique ^c   Itchaï, Carole ^a   Amaro, José ^a   Hofman, Paul ^a  

^a Centre Hospitalier Robert Ballanger CHRB   (France)

^b PASTEUR HOSPITAL   (France)

^c University Hospital of Nice University of Nice Sophia Antipolis   (France)

Author keywords

AIDS; Electron microscopy; Lactic acidosis; Mitochondrial toxicity; Nucleoside analogues; Steatosis

Indexed keywords

DIDANOSINE; NELFINAVIR; NUCLEOSIDE DERIVATIVE; STAVUDINE;

ABDOMINAL PAIN; ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; FATTY LIVER; HEPATOMEGALY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LACTIC ACIDOSIS; LIVER CELL; MITOCHONDRION; PATHOLOGY; TACHYPNEA; VOMITING;

ACIDOSIS, LACTIC; ADULT; ANTI-HIV AGENTS; ANTIMETABOLITES; DIDANOSINE; FATAL OUTCOME; FATTY LIVER; FEMALE; HIV SEROPOSITIVITY; HUMANS; LAMIVUDINE; MICROSCOPY, ELECTRON; MITOCHONDRIA, LIVER; STAVUDINE; ZIDOVUDINE;

EID: 0035007044     PISSN: 02426498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. The liver in AIDS
2. Hepatomegaly with severe steatosis in HIV-seropositive patients
3. Zidovudine-associated type B lactic acidosis and hepatic steatosis in an HIV-infected patient
4. Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion
5. Acidose lactique et altérations mitochondriales hépatiques au cours d'un traitement par zidovudine
6. Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine
7. Hepatic steatosis and latic acidosis associated with stavudine treatment in an HIV patient: A case report
8. Lactic acidosis associated with stavudine administration: A report of five cases
9. Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy (case report)
10. Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as common pathway