Different host-cell shutoff strategies related to the matrix protein lead to persistence of vesicular stomatitis virus mutants on fibroblast cells

Virus Research

Volumn 76, Issue 1, 2001, Pages 87-102

  Desforges, Marc ^a,c   Charron, Josée ^a   Bérard, Stéphane ^a   Beausoleil, Sylvain ^a   Stojdl, David F ^b   Despars, Geneviève ^a   Laverdière, Bernard ^a   Bell, John C ^b   Talbot, Pierre J ^c   Stanners, Clifford P ^d   Poliquin, Laurent ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b OTTAWA REGIONAL CANCER CENTRE   (Canada)

^c INRS INSTITUT ARMAND FRAPPIER   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Host cell shutoff; Matrix protein; Vesicular stomatitis virus; Viral persistence

Indexed keywords

MATRIX PROTEIN; MUTANT PROTEIN; RNA; VIRUS ANTIGEN; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN DETECTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN L 929; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; FIBROBLAST CULTURE; GENE EXPRESSION; GENE MUTATION; HOST CELL; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; RNA SYNTHESIS; STRAIN DIFFERENCE; TEMPERATURE SENSITIVE MUTANT; VERO CELL; VESICULAR STOMATITIS VIRUS; VIRUS CELL INTERACTION; VIRUS MUTANT; VIRUS STRAIN;

ANIMALS; CELL SIZE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DOWN-REGULATION; FIBROBLASTS; L CELLS (CELL LINE); MICE; MUTATION; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, MESSENGER; RNA, VIRAL; VERO CELLS; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL MATRIX PROTEINS; VIRAL PROTEINS; VIRUS REPLICATION;

VESICULAR STOMATITIS VIRUS;

EID: 0035005593     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1702(01)00251-9     Document Type: Article

References (42)

1. Ahmed M., Lyles D.S. Identification of a consensus mutation in M protein of vesicular stomatitis virus from persistently infected cells that affects inhibition of host-directed gene expression. Virology. 237:1997;378-388.
2. Black B.L., Lyles D.S. Vesicular stomatitis virus matrix protein inhibits host cell-directed transcription of target genes in vivo. J. Virol. 66:1992;4058-4064.
3. Black B.L., Rhodes R.B., McKenzie M., Lyles D.S. The role of vesicular stomatitis virus matrix protein in inhibition of host-directed gene expression is genetically separable from its function in virus assembly. J. Virol. 67:1993;4814-4821.
4. Blondel D., Harmison G.G., Schubert M. Role of matrix protein in cytopathogenesis of vesicular stomatitis virus. J. Virol. 64:1990;1716-1725.
5. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched with ribonuclease. Biochemistry. 18:1979;5294-5300.
6. Cory A.H., Owen T.C., Barltrop J.A., Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3:1991;207-212.
7. Coulon P., Deutsch V., Lafay F., Martinet-Edelist C., Wyers F., Herman R.C., Flamand A. Genetic evidence for multiple functions of the matrix protein of vesicular stomatitis virus. J. Gen. Virol. 71:1990;991-996.
8. Farmilo A.J., Stanners C.P. Mutant of vesicular stomatitis virus which allows deoxyribonucleic acid synthesis and division in cells synthesizing viral ribonucleic acid. J. Virol. 10:1972;605-613.
9. Ferran M.C., Lucas-Lenard J.M. The vesicular stomatitis virus matrix protein inhibits transcription from the human β-interferon promoter. J. Virol. 71:1997;371-377.
10. Flamand A. Étude génétique du virus de la stomatite vésiculaire: Classement de mutants thermosensibles spontanés en groupe de complémentation. J. Gen. Virol. 8:1970;187-195.
11. Foley K.P., Leonard M.W., Engel J.D. Quantitation of RNA using the polymerase chain reaction. Technical focus. Trends Genet. 9:1993;380-384.
12. Francoeur A.M., Poliquin L., Stanners C.P. The isolation of interferon-inducing mutants of vesicular stomatitis virus with altered viral P function for the inhibition of total protein synthesis. Virology. 160:1987;236-245.
13. Genty N. Modifications induced by VSV and ts mutants in chick embryo cell permeation. Mahy B.W.J., Barry R.D. Negative Strand Viruses and the Host Cell. 1978;833-840 Academic press, London, New York and San Franscisco.
14. Gopalakrishna Y., Lenard J. Sequence alterations in temperature-sensitive M-protein mutants (complementation group III) of vesicular stomatitis virus. J. Virol. 56:1985;655-659.
15. Holland J.J., Villarreal L.P. Persistent noncytocidal vesicular stomatitis virus infections mediated by defective T particles that suppress virion transcriptase. Proc. Natl. Acad. Sci. USA. 71:1974;2956-2960.
16. Huprikar J., Rabinowitz S.G., Dal Canto M.C., Rundell M.K. Persistent infection of temperature-sensitive G31 vesicular stomatitis virus mutant in neural and nonneural cells: biological and virological characteristics. J. Virol. 58:1986;493-499.
17. Justice P.A., Sun W., Li Y., Ye Z., Grigera P.R., Wagner R.R. Membrane vesiculation function and exocytosis of wild-type and mutant matrix proteins of vesicular stomatitis virus. J. Virol. 69:1995;3156-3160.
18. Knipe D., Lodish H.F., Baltimore D. Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific viral proteins. J. Virol. 21:1977;1140-1148.
19. Koyama A.H. Induction of apoptotic DNA fragmentation by the infection of vesicular stomatitis virus. Virus Res. 37:1995;285-290.
20. Lyles D.S., McKenzie M.O. Activity of vesicular stomatitis virus M protein mutants in cell rounding is correlated with the ability to inhibit host gene expression and is not correlated with virus assembly function. Virology. 229:1997;77-89.
21. Lyles D.S., McKenzie M.O., Ahmed M., Woolwine S.C. Potency of wild-type and temperature-sensitive vesicular stomatitis virus matrix protein in the inhibition of host-directed gene expression. Virology. 225:1996;172-180.
22. Marcus P.I., Sekellick M.J. Cell killing by viruses III. The interferon system and inhibition of cell killing by vesicular stomatitis virus. Virology. 69:1977;378-393.
23. Morita K., Vanderoef R., Lenard J. Phenotypic revertants of temperature-sensitive M protein mutants of vesicular stomatitis virus: sequence analysis and functional characterization. J. Virol. 61:1987;256-263.
24. Nishiyama Y. Studies of L cells persistently infected with VSV: factors involved in the regulation of persistent infection. J. Gen. Virol. 35:1977;265-279.
25. Potter, K.M., and Stewart, R.B., (1976). Comparison of vesicular stomatitis virus defective interfering particle synthesis in chick embryo and L cells. Can. J. Microbiol. 22 (10), 1458-1463.
26. Preble O.T., Youngner J.S. Temperature-sensitive viruses and the etiology of chronic and inapparent infections. J. Infect. Dis. 131:1975;467-473.
27. Pringle C.R. The genetics of vesiculoviruses. Arch. Virol. 19:1982;90-101.
28. Pringle C.R. Rhabdoviruses genetics. The Rhabdoviruses. 1987;167-243 Plenum Press, New York.
29. Rabinowitz S.G., DalCanto M.C., Johnson T.C. Comparison of central nervous system disease produced by wild-type and temperature-sensitive mutants of vesicular stomatitis virus. Infect. Immun. 13:1976;1242-1249.
30. Ramseur J.M., Friedman R.M. Prolonged infection of interferon-treated cells by vesicular stomatitis virus: possible role of temperature-sensitive mutants and interferon. J. Gen. Virol. 37:1977;523-533.
31. Rima B.K., Davidson W.B., Martin S.J. The role of defective interfering particles in persistent infection of Vero cells by measles virus. J. Gen. Virol. 35:1977;89-97.
32. Rose J.K., Gallione C.J. Nucleotide sequences of the mRNA's encoding the vesicular stomatitis virus G and M proteins determined from cDNA clones containing the complete coding regions. J. Virol. 39:1981;519-528.
33. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
34. Sekellick M.J., Marcus P.I. Persistent infection. II. Interferon-inducing temperature-sensitive mutants as mediators of cell sparing: possible role in persistent infection by vesicular stomatitis virus. Virology. 95:1979;36-47.
35. Stanners C.P., Farmilo A.J., Goldberg V.J. Effects in vitro and in vivo of a mutant of vesicular stomatitis virus with attenuated cytopathogenicity. Mahy B.W.J., Barry R.D. Negative Strand Viruses. 1975;785-798 Academic Press, London.
36. Stanners C.P., Kennedy S., Poliquin L. Vesicular stomatitis virus P function depends on cellular growth cycle. Virology. 160:1987;255-258.
37. Verani P., Nicoletti L., Marchi A. Establishment and maintenance of persistent infection by phlebovirus toscana in Vero cells. J. Gen. Virol. 65:1984;367-375.
38. Wagner R.R. The Rhabdoviruses. 1987;Plenum Press, New York.
39. Wagner R.R. Rhabdoviridae and their replication. Fields B.N., Knipe D.M., et al. In Fundamental Virology. second ed. 1991;Raven Press, New York.
40. Whitaker-Dowling P., Younger J.S., Widnell C.C., Wilcox D.K. Superinfection exclusion by vesicular stomatitis virus. Virology. 131:1983;137-143.
41. Youngner J.S., Dubovi E.J., Quagliana D.O., Kelly M., Preble O.T. Role of temperature-sensitive mutants in persistent infections initiated with the vesicular stomatitis virus. J. Virol. 19:1976;90-101.
42. Youngner J.S., Preble O.T., Jones E.V. Persistent infection of L cells with vesicular stomatitis virus: evolution of virus population. J. Virol. 28:1978;6-13.