Increased transgene expression by the mouse tyrosinase enhancer is restricted to neural crest-derived pigment cells

Genesis

Volumn 29, Issue 4, 2001, Pages 180-187

  Camacho Hbner, Agns ^a   Beermann, Friedrich ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

LacZ; Melanoblast; Melanocyte; RPE; Toxin; Tyrosinase

Indexed keywords

DIPHTHERIA TOXIN; MONOPHENOL MONOOXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL LINEAGE; CHOROID; CONTROLLED STUDY; EMBRYO DEVELOPMENT; ENHANCER REGION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; MELANOCYTE; MOUSE; NEURAL CREST; NONHUMAN; PIGMENT CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REPORTER GENE; TELENCEPHALON; TRANSGENE;

ANIMALS; ARTIFICIAL GENE FUSION; DIPHTHERIA TOXIN; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION, DEVELOPMENTAL; LAC OPERON; MELANOCYTES; MICE; MICE, TRANSGENIC; MONOPHENOL MONOOXYGENASE; NEURAL CREST; PHENOTYPE; PIGMENT EPITHELIUM OF EYE; PIGMENTATION; TRANSGENES;

EID: 0035003440     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1022     Document Type: Article

References (40)

1. Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis
2. Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice
3. Expression of the mouse tyrosinase gene during embryonic development: Recapitulation of the temporal regulation in transgenic mice
4. Caractéristiques cellulaires et moléculaires de la pigmentation chez les mammifères-tyrosinase et TRP
5. The Fugu rubripes tyrosinase gene promoter targets transgene expression to pigment cells in the mouse
6. The gene encoding the T-box factor Tbx2 is a target for the Microphthalmia-associated transcription factor in melanocytes
7. Cooperative effects of INK4a and ras in melanoma susceptibility in vivo
8. Essential role for oncogenic ras in tumor maintenance
9. Tyrosinase and related proteins in mammalian pigmentation
10. A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice
11. Analysis of the mouse tyrosinase promoter in vitro and in vivo
12. The mouse tyrosinase gene: Promoter modulation by positive and negative regulatory elements
13. The use of yeast artificial chromosomes in transgenic animals: Expression studies of the tyrosinase gene in transgenic mice
14. Mitf from neural crest to melanoma: Signal transduction and transcription in the melanocyte lineage
15. Activation of a diphtheria toxin A gene by expression of human immunodeficiency virus-1 Tat and Rev proteins in transfected cells
16. Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras
17. Nomenclature for identified pigmentation genes in the mouse
18. The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina
19. Strain-specific white-spotting patterns in laboratory mice
20. Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo
21. Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox176 attenuated diphtheria toxin A chain
22. A locus control region at -12 kb of the tyrosinase gene
23. Endothelin signalling in the development of neural crest-derived melanocytes
24. High-molecular weight forms of tyrosinase and the tyrosinase-related proteins: Evidence for a melanogenic complex
25. Distal upstream tyrosinase S/MAR-containing sequence has regulatory properties specific to subsets of melanocytes
26. Mosaicism of tyrosinase-locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygous chinchilla-mottled mice
27. A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: Position-independent and mosaic expression
28. The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina
29. A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
30. LacZ transgenic mice to monitor gene expression in embryo and adult
31. Ectopic expression of ret results in microphthalmia and tumors in the retinal pigment epithelium
32. The temporal requirement for endothelin receptor-B signalling during neural crest development
33. TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor
34. Tyrosinase is a new marker for cell populations in the mouse neural tube
35. Regulation of the tyrosinase promoter in transgenic mice: Expression of a tyrosinase-lacZ fusion gene in embryonic and adult brain
36. New evidence for presence of tyrosinase in substantia nigra, forebrain and midbrain
37. Receptor tyrosine kinase-dependent neural crest migration in response to differentially localized growth factors
38. Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway
39. Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice
40. Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues