Multidrug transport by ATP binding cassette transporters: A proposed two-cylinder engine mechanism

Research in Microbiology

Volumn 152, Issue 3-4, 2001, Pages 365-374

  Van Veen, Hendrik W ^a,c   Higgins, Christopher F ^b   Konings, Wil N ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c Univ of C   (United Kingdom)

Author keywords

ABC transporter; Drug binding site; Multidrug resistance; Transport mechanism

Indexed keywords

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTHRACYCLINE; BUCLADESINE; CALCIUM CHANNEL BLOCKING AGENT; CARBOXYFLUORESCEIN; COLCHICINE; DACTINOMYCIN; EPIPODOPHYLLOTOXIN DERIVATIVE; FLUPENTIXOL; GLUCURONIDE; GLUTATHIONE; GLYCOPROTEIN P; IMMUNOSUPPRESSIVE AGENT; LIPID; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; NITROGEN; PACLITAXEL; PEPTIDE; PHOSPHONIUM DERIVATIVE; STEROID HORMONE; SULFATE; TAUROCHOLIC ACID; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNINDEXED DRUG; VANADIC ACID; VINBLASTINE; VINCA ALKALOID;

ARTICLE; BINDING SITE; DRUG TRANSPORT; HUMAN; HYDROLYSIS; LIPOPHILICITY; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BINDING SITES; DRUG RESISTANCE, MICROBIAL; DRUG RESISTANCE, MULTIPLE; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS);

EID: 0035002975     PISSN: 09232508     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2508(01)01208-6     Document Type: Article

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