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Volumn 17, Issue 2, 2001, Pages 393-410

New approaches to diagnose and treat Alzheimer's disease : A glimpse of the future

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; BIOLOGICAL MARKER;

EID: 0035001457     PISSN: 07490690     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0749-0690(05)70075-6     Document Type: Article
Times cited : (22)

References (79)
  • 6
    • 0033835996 scopus 로고    scopus 로고
    • Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    • (2000) Nat Med , vol.6 , pp. 916
    • Bard, F.1    Cannon, C.2    Barbour, R.3
  • 9
    • 0034595821 scopus 로고    scopus 로고
    • Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia
    • (2000) J Biol Chem , vol.275 , pp. 16941
    • Brazil, M.I.1    Chung, H.2    Maxfield, F.R.3
  • 10
    • 14444272986 scopus 로고    scopus 로고
    • Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor
    • (1998) J Biol Chem , vol.273 , pp. 27765
    • Buxbaum, J.D.1    Liu, K.N.2    Luo, Y.3
  • 15
  • 16
    • 0034099077 scopus 로고    scopus 로고
    • Using serial registered brain magnetic resonance imaging to measure disease progression in Alzheimer disease: Power calculations and estimates of sample size to detect treatment effects
    • (2000) Arch Neurol , vol.57 , pp. 339
    • Fox, N.C.1    Cousens, S.2    Scahill, R.3
  • 18
    • 15644363081 scopus 로고    scopus 로고
    • High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype
    • (1998) Arch Neurol , vol.55 , pp. 937
    • Galasko, D.1    Chang, L.2    Motter, R.3
  • 26
  • 32
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
    • (1993) Cell , vol.73 , pp. 1055
    • Jarrett, J.T.1    Lansbury P.T., Jr.2
  • 34
  • 43
    • 0034213718 scopus 로고    scopus 로고
    • High-level neuronal expression of abeta 1-42 in wildtype human amyloid protein precursor transgenic mice: Synaptotoxicity without plaque formation
    • (2000) J Neurosci , vol.20 , pp. 4050
    • Mucke, L.1    Masliah, E.2    Yu, G.Q.3
  • 45
    • 0034704547 scopus 로고    scopus 로고
    • Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: A randomized controlled trial. Alzheimer's Disease Cooperative Study
    • (2000) JAMA , vol.283 , pp. 1007
    • Mulnard, R.A.1    Cotman, C.W.2    Kawas, C.3
  • 46
  • 53
    • 4243363012 scopus 로고    scopus 로고
    • Increased isoprostane biosynthesis in Alzheimer's disease: Correlation of a specific non invasive index of lipid peroxidation with disease severity
    • (2000) Neurobiol Aging , vol.21 , Issue.SUPPL. 1
    • Pratico, D.1    Clark, C.C.2    Lee, V.-M.3
  • 57
    • 0030967165 scopus 로고    scopus 로고
    • A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
    • (1997) N Engl J Med , vol.336 , pp. 1216
    • Sano, M.1    Ernesto, C.2    Thomas, R.G.3
  • 61
    • 16044373524 scopus 로고    scopus 로고
    • Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
    • (1996) Nat Med , vol.2 , pp. 864
    • Scheuner, D.1    Eckman, C.2    Jensen, M.3
  • 62
    • 0031454126 scopus 로고    scopus 로고
    • Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease: A proton MR spectroscopic imaging and MRI study
    • (1997) Neurology , vol.49 , pp. 1513
    • Schuff, N.1    Amend, D.2    Ezekiel, E.3
  • 63
    • 0033600274 scopus 로고    scopus 로고
    • Translating cell biology into therapeutic advances in Alzheimer's disease
    • (1999) Nature , vol.399 , Issue.6738 SUPPL.
    • Selkoe, D.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.