Myocardial stunning in exercise-induced ischemia in dogs: Lack of late preconditioning

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 1 49-1, 2001, Pages

  De Curzon, Olivier Parent ^a   Ghaleh, Bijan ^a   Tissier, Renaud ^a   Giudicelli, Jean François ^a,c   Hittinger, Luc ^b   Berdeaux, Alain ^a  

^a INSERM   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Conscious dogs; Coronary stenosis; High flow ischemia; Second window of preconditioning

Indexed keywords

ACETYLCHOLINE; GLYCERYL TRINITRATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY OBSTRUCTION; DOG; EXERCISE; HEART INFARCTION PREVENTION; HEART MUSCLE ISCHEMIA; HYPEREMIA; NONHUMAN; PRIORITY JOURNAL; STUNNED HEART MUSCLE; TREADMILL EXERCISE;

EID: 0035001034     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.1.h302     Document Type: Article

References (25)

1. Mechanism of myocardial stunning
2. Basic and clinical aspects of myocardial stunning
3. The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase: Evidence that nitric oxide acts both as trigger and as a mediator of the late phase of ischemic preconditioning
4. Molecular and cellular mechanisms of myocardial stunning
5. Effect of tachycardia on regional function and transmural myocardial perfusion during graded coronary pressure reduction in conscious dogs
6. Systemic and regional hemodynamics assessment in rats with fluorescent microsphere
7. Regional myocardial functional and electrophysiological alterations after brief coronary artery occlusion in conscious dogs
8. Effect of superoxide dismutase and catalase on regional dysfunction after exercise-induced ischemia
9. Persistence of regional left ventricular dysfunction after exercise-induced myocardial ischemia
10. Subendocardial and subepicardial wall thickening in exercising dogs
11. Delayed enhanced nitric oxide-mediated coronary vasodilation following brief ischemia and prolonged reperfusion in conscious dogs
12. Endocardial and epicardial infarct size after preconditioning by a partial coronary artery occlusion without intervening reperfusion: Importance of the degree and duration of flow reduction
13. Preconditioning improves energy metabolism during reperfusion but does not attenuate myocardial stunning in porcine hearts
14. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
15. Myocardial protection is lost before contractile function recovers from ischemic preconditioning
16. Myocardial reactive hyperemia in the unanesthetized dog
17. Preconditioning does not attenuate myocardial stunning
18. Ischemic preconditioning reduces infarct size in swine myocardium
19. Direct evidence that hydroxyl radical plays a pathogenetic role in myocardial "stunning" in the conscious dog and demonstration that stunning can be markedly attenuated without subsequent adverse effects
20. Differences in myocardial stunning following coronary artery occlusion in conscious dogs, pigs, and baboons
21. Late preconditioning against myocardial stunning: An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs
22. Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs
23. Time course of late preconditioning against myocardial stunning in conscious pigs
24. Characteristics of regional myocardial stunning after exercise in dogs with chronic coronary stenosis
25. Regional myocardial dysfunction and hemodynamic abnormalities during strenuous exercise in dogs with limited coronary flow