Nimesulide: Overview of properties and applications

Drugs of Today

Volumn 37, Issue SUPPL. B, 2001, Pages 3-7

  Rainsford, K D ^a  

^a SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; CYTOCHROME P450; DRUG DERIVATIVE; NIMESULIDE; ROFECOXIB;

ANALGESIA; ANTIINFLAMMATORY ACTIVITY; CONFERENCE PAPER; DRUG INDICATION; DRUG METABOLISM; DRUG SAFETY; DRUG STRUCTURE; GASTROINTESTINAL TRACT; HUMAN; LIVER TOXICITY; METABOLITE; MUSCULOSKELETAL DISEASE; OSTEOARTHRITIS; PKA; SKIN MANIFESTATION; STEVENS JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS;

EID: 0034999761     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

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7. Maffei Facino, R., Carini, M., Aldini, G., Saibene, L., Morelli, R. Differential inhibition of superoxide, hydroxyl and peroxyl radicals by nimesulide and its main metabolite 4-hydroxynimesulide. Forzneim-Forsch 1995, 45: 1102-9.
8. Bernareggi, A. Pharmacokinetics of nimesulide. Clin Pharmacokinet 1998, 35 (4): 247-74.
9. Rainsford, K.D. An analysis from clinico-epidemiological data of the principal adverse events from the COX-2 selective NSAID, nimesulide, with particular reference to hepatic injury, Inflammopharmacology 1998, 6: 203-21.
10. Rainsford, K.D. Relationship of nimesulide safety to its pharmacokinetics: Assessment of adverse reactions. Rheumatology 1999, 38 (Suppl. 1): 4-10.
11. Rainsford, K.D. Hepato-renal effects of NSAIDs. In: International Conference on Inflammopharmacology with VIIth Symposium on Side-Effects of Anti-inflammatory Drugs. (Sheffield Sept. 10.13, 2000) Abst. 14.