Epigenetic targeting in the mouse zygote marks DNA for later methylation: A mechanism for maternal effects in development

Mechanisms of Development

Volumn 103, Issue 1-2, 2001, Pages 35-47

  Pickard, Benjamin ^a   Dean, Wendy ^a   Engemann, Sabine ^b   Bergmann, Kerstin ^b   Fuermann, Martina ^b   Jung, Martin ^d   Reis, Andre ^d   Allen, Nick ^a   Reik, Wolf ^a   Walter, Jörn ^b,c  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Backcross; Chromatin; Epigenetics; Epistasis; Imprinting; Maternal effect; Modifiers; Oocyte cytoplasm; Parent of origin effect; Position effect; Pronuclear transplantation; Strain specific transgene methylation

Indexed keywords

EXTRACHROMOSOMAL DNA;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DNA TRANSFECTION; EMBRYO; EMBRYO DEVELOPMENT; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENE TARGETING; GENOME IMPRINTING; GENOTYPE; MALE; MOTHER FETUS RELATIONSHIP; MOUSE; NIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TECHNIQUE; TRANSGENIC MOUSE;

ALLELES; ANIMALS; CELL NUCLEUS; CHROMOSOME MAPPING; CROSSES, GENETIC; CYTOPLASM; DNA METHYLATION; FEMALE; FERTILIZATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC MARKERS; GENOMIC IMPRINTING; GENOTYPE; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, TRANSGENIC; MICROSATELLITE REPEATS; MODELS, BIOLOGICAL; MODELS, GENETIC; MOTHERS; PHENOTYPE; TRANSGENES;

EID: 0034998943     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00329-X     Document Type: Article

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