Type 1 diabetes mellitus, celiac disease and their association - Lessons from antibodies

Journal of Pediatric Endocrinology and Metabolism

Volumn 14, Issue SUPPL. 1, 2001, Pages 607-610

  Hummel, M ^a   Ziegler, Anette G ^a,c   Bonifacio, E ^b  

^a Klinikum Schwabing   (Germany)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c INSTITUT FÜR DIABETESFORSCHUNG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; ENDOMYSIUM ANTIBODY; GLIADIN ANTIBODY; GLUTEN; HLA ANTIGEN; IMMUNOGLOBULIN G4;

ARTICLE; BIOPSY; CELIAC DISEASE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC MARKER; GLUTEN FREE DIET; HUMAN; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; MALE; OSTEOPOROSIS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PATHOGENICITY; RELATIVE; SCREENING;

EID: 0034997640     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/jpem.2001.14.s1.607     Document Type: Article

References (14)

1. Ziegler AG, Hummel M, Schenker M, Bonifacio E. Autoantibody appearance and risk for the development of childhood diabetes in offspring of parents with type 1 diabetes: the two year analysis of the BABYDIAB study. Diabetes 1999; 48: 460-468.
2. Naserke HE, Ziegler AG, Lampasona V, Bonifacio E. Early development and spreading of autoantibodies to epitopes of IA-2 and their association with progression to type 1 diabetes. J Immunol 1998; 161: 6963-6969.
3. Bonifacio E, Scirpoli M, Kredel K, Füchtenbusch M, Ziegler AG. Early autoantibody responses in prediabetes are IgGl dominated and suggest antigen-specific regulation. J Immunol 1999; 163: 525-532.
4. Schenker M, Hummel M, Ferber K, Walter M, Keller E, Albert ED, Janka HU, Kastendiek C, Sorger M, Louwen F, Ziegler AG. Early expression and high prevalence of islet autoantibodies for DR3/4 heterozygous and DR4/4 homozygous offspring of parents with type 1 diabetes: the German BABYDIAB study. Diabetologia 1999; 42: 671-677.
5. Hummel M, Füchtenbusch M, Schenker M, Ziegler AG. No major association of breast feeding, vaccinations and common childhood viral disease with early islet autoimmunity in the German BABY-DIAB Study. Diabetes Care 2000; 23: 969-974.
6. Cronin CC, Shanahan F. Insulin-dependent diabetes mellitus and coeliac disease. Lancet 1997; 349: 1096-1097.
7. Trier JC. Celiac sprue. N Engl J Med 1991; 325: 1709-1719.
8. Bonifacio E, Ziegler AG, Hummel M, Dittler J, Lampasona V, Pastore MR, Bosi E. Gluten: is it also a determinant of islet autoimmunity? Diabetes Metab Rev 1998; 14: 259-260.
9. Dieterich W, Laag E, Schöpper H, Volta U, Ferguson A, Gillett H, Rieken EO, Schuppan D. Autoantibodies to tissue transglutaminase as predictors of celiac disease. Gastroenterology 1998; 115: 1317-1321.
10. Lampasona V, Bonfanti R, Bazzigaluppi E, Venerando A, Chiumello G, Bosi E, Bonifacio E. Antibodies to tissue transglutaminase C in type 1 diabetes. Diabetologia 1999; 42: 1195-98.
11. Hummel M, Bonifacio E, Stern M, Dittler J, Schimmel A, Ziegler AG. Development of celiac disease associated antibodies in offspring of parents with type 1 diabetes. Diabetologia 2000; 43: 1005-1011.
12. Meloni G, Dore A, Fanciulli G, Tanda F, Bottazzo GF. Subclinical coeliac disease in schoolchildren from northern Sardinia. Lancet 1999; 353: 37.
13. Bao F, Yu L, Babu S, Wang T, Hoffenberg EJ, Rewers M, Eisenbarth GS. One third of HLA DQ2 homozygous patients with type 1 diabetes express celiac disease-associated transglutaminase autoantibodies. J Autoimmun 1999; 13: 143-148.
14. Ventura A, Magazzu G, Greco L, SIGEP Study Group. Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. Gastroenterology 1999; 117: 297-303.