Expression of inducible nitric oxide synthase in the cochlea following immune response in the endolymphatic sac of guinea pigs

ORL

Volumn 63, Issue 3, 2001, Pages 155-159

  Watanabe, Ken Ichi ^a   Tomiyama, Shunichi ^a   Jinnouchi, Ken ^a   Pawankar, Ruby ^a   Yagi, Toshiaki ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Endolymphatic hydrops; Endolymphatic sac; Immune response; Inducible nitric oxide synthase

Indexed keywords

KEYHOLE LIMPET HEMOCYANIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COCHLEA; CONTROLLED STUDY; CORTI ORGAN; ENDOLYMPHATIC SAC; GUINEA PIG; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INNER EAR DISEASE; MENIERE DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPIRAL GANGLION; STRIA VASCULARIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; COCHLEA; ENDOLYMPHATIC SAC; GUINEA PIGS; HEMOCYANIN; IMMUNOHISTOCHEMISTRY; NITRIC OXIDE SYNTHASE;

EID: 0034997458     PISSN: 03011569     EISSN: None     Source Type: Journal    
DOI: 10.1159/000055732     Document Type: Article

References (21)

1. Moncada S, Palmer R, Higgs E: Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142.
2. Knowles RG, Moncada S: Nitric oxide synthases in mammals. Biochem J 1994;298:249-258.
3. Takumida M, Anniko M: Lipopolysaccharide-induced expression of nitric oxide synthase II in the guinea pig vestibular end organ. Eur Arch Otorhinolaryngol 1998;255:184-188.
4. Hess A, Bloch W, Huverstuhl J, Su J, Stennert E. Addicks K, Michel O: Expression of inducible nitric oxide synthase (iNOS/NOS II) in the cochlea of guinea pigs after intratympanical endotoxin-treatment. Brain Res 1999;830: 113-122.
5. Watanabe K, Hess A, Bloch W, Michel O: Expression of inducible nitric oxide synthase (iNOS/NOS II) in the vestibule of guinea pigs after the application of cisplatinum (CDDP). Anticancer Drugs 2000;11:29-32.
6. Tomiyama S: Development of endolymphatic hydrops following immune response in the endolymphatic sac of the guinea pig. Acta Otolaryngol 1992;112:470-478.
7. Kimura RS, Schuknecht HF: Membranous hydrops in the inner ear of the guinea pig after obliteration of the endolymphatic sac. Pract
8. Wackym PA, Friberg U, Linthicum FH, Sjöbäck DB, Bui HT, Hofman FH, Rask-Andersen H: Human endolymphatic sac: Morphological evidence of immunologic function. Ann Otol Rhinol Laryngol 1987;96:276-281.
9. Nonaka M, Tomiyama S, Gotoh Y, Ikezono T, Yagi T: Vestibular disorder following immune response of the endolymphatic sac in the guinea pig. Ann Otol Rhinol Laryngol 1992; 104(suppl 157):54-57.
10. Tomiyama S: Endolymphatic hydrops induced by immune response of the endolymphatic sac: Its relation to perilymph antibody levels. Ann Otol Rhinol Laryngol 1992:101(suppl 157):48-53.
11. Tomiyama S, Nonaka M, Gotoh Y, Ikezono T, Yagi T: Immunological approach to Méniére's disease: Vestibular immune injury following immune reaction of the endolymphatic sac. ORL 1994;56:11-18.
12. Tomiyama S, Yagi T, Sakagami M, Fukazawa K: Immunological pathogenesis of endolymphatic hydrops and its relation to Ménière's disease. Scanning Microsc 1993;7:907-920.
13. Hess A, Bloch W, Su J, Stennert E, Addicks K, Michel O: Expression of inducible nitric oxide-synthase in the vestibular system of hydropic guinea pigs. Neurosci Lett 1999;264:145-148.
14. Arnhold S, Andressen C, Bloch W, Mai JK, Addicks K: NO synthase-II is transiently expressed in embryonic mouse olfactory receptor neurons. Neurosci Lett 1997;229:165-168.
15. Fessenden JS, Schacht J: The nitric oxide/ cyclic GMP pathway: A potential major regulator of cochlear physiology. Hear Res 1998;118: 168-176.
16. Tanaka H, Kijima H, Tokunaga T, Tajima T, Himeno S, Kenmochi T, Oshiba G, Kise Y, Nishi T, Chino O, Shimada H, Machimura T, Tanaka M, Makuuchi H: Frequent expression of inducible nitric oxide synthase in esophageal squamous cell carcinomas. Int J Oncol 1999; 14:1069-1073.
17. Manzoni O, Prezeau L, Marin P, Deshager S, Bockaert J, Fagni L: Nitric oxide-induced blockade of NMDA receptors. Neuron 1992;8: 653-662.
18. Estrem SA, Babin RW, Ryu JH, Moore KC: Cis-diamminc dichloroplatinum (11) ototoxicity in the guinea pig. Otolaryngol Head Neck Surg 1981;89:638-645.
19. Takahashi M, Tomiyama S: Immunohistochemical study of endolymphatic hydrops due to secondary immune endolymphatic sac immune reaction. Nippon Jibiinkoka Gakkai Kaiho (Tokyo) 1990;93:1372-1378.
20. Li W, Lin J, Adams GL, Juhn SK: Expression of inducible nitric oxide synthase (iNOS) in middle ear epithelial cells by IL-1 beta and TNF-alpha. Int J Pediatr Otorhinolaryngol 2000;55:91-98.
21. Aran JW, Rarey KE, Hawkins Jr JE: Functional and morphological changes in experimental endolymphatic hydrops. Acta Otolaryngol 1984;97:547-557.