Sulfate and chloride transport in Caco-2 cells: Differential regulation by thyroxine and the possible role of DRA gene

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 280, Issue 4 43-4, 2001, Pages

  Alrefai, W A ^a   Tyagi, S ^a   Mansour, F ^a   Saksena, S ^a   Syed, I ^a   Ramaswamy, K ^a   Dudeja, P K ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Anion exchangers; Cl HCO3 (OH ) exchange; Human intestine; SO42 OH exchange

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CHLORIDE; MESSENGER RNA; NITRATE; OXALIC ACID; RIBONUCLEASE; SHORT CHAIN FATTY ACID; SULFATE; THYROXINE;

ARTICLE; CELL STRAIN CACO 2; CHLORIDE TRANSPORT; DOWN REGULATION; DRA GENE; GENE; HUMAN; HUMAN CELL; ION EXCHANGE; PRIORITY JOURNAL;

EID: 0034997015     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2001.280.4.g603     Document Type: Article

References (40)

1. Alper SL. The band 3-related AE anion exchanger gene family. Cell Physiol Biochem 4: 265-281, 1994.
2. Alrefai WA, Barakat J, Tyagi S, Layden TJ, Ramaswamy K, and Dudeja PK. AE-2 and AE-3 anion exchanger isoforms are localized to the basolateral but not the apical membranes in the human intestine (Abstract). Gastroenterology 111: A344, 1997.
3. Bieberdorf FA, Gordon P, and Fordtran JS. Pathogenesis of congenital alkalosis with diarrhea: implications for the physiology of normal ileal electrolyte absorption and secretion. J Clin Invest 51: 1958-1968, 1972.
4. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
5. Cabantchik ZI and Greger R. Chemical probes for anion transporters of mammalian cell membranes. Am J Physiol Cell Physiol 262: C803-C827, 1992.
6. Cano A, Baum M, and Moe OW. Thyroid hormone stimulates the renal Na/H exchanger NHE3 by transcriptional activation. Am J Physiol Cell Physiol 276: C102-C108, 1999.
7. Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
8. Chou H, Passage M, and Jonas AJ. Regulation of lysosomal sulfate transport by thyroid hormone. J Biol Chem 269: 23524-23529, 1994.
9. Chow A, Dobbins JW, Aronson PS, and Igarashi P. cDNA cloning and localization of a band 3 related protein from ileum. Am J Physiol Gastrointest Liver Physiol 263: G345-G352, 1992.
10. 3 exchanger during intestinal development. Am J Physiol Gastrointest Liver Physiol 271: G330-G337, 1996.
11. Dudeja PK, Hafez N, Tyagi S, Gailey CA, Toofanfard M, Alrefai WA, Nazir TM, Ramaswamy K, and Al-Bazzaz, FJ. Expression of the Na+/H+ and Cl-/HCO-3 exchanger isoforms in proximal and distal human airways. Am J Physiol Lung Cell Mol Physiol 276: L971-L978, 1999.
12. Goldfine ID, Simons CG, Smith GJ, and Ingbar SH. Cycloleucine transport in isolated rat thymocytes: in vitro effects of triiodothyronine and thyroxine. Endocrinology 96: 1030-1037, 1975.
13. Harig JM, Soergel KH, Barry JA, and Ramaswamy K. Transport of propionate by human ileal brush-border membrane vesicles. Am J Physiol Gastrointest Liver Physiol 260: G776-G782, 1991.
14. Henning SJ. Ontogeny of enzymes in the small intestine. Annu Rev Physiol 47: 231-245, 1985.
15. Hoglund P. Positional candidate genes for congenital chloride diarrhea suggested by high-resolution physical mapping in chromosome region 7q31. Genome Res 6: 202-210, 1996.
16. Hoglund P, Haila S, Socha J, Tomaszewski L, Saarialhokere U, Lindsberg MLK, Chapelle A, and Kere J. Mutations of the down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea. Nat Genet 14: 316-319, 1996.
17. Kere J, Lohi H, and Hoglund P. Genetic disorders of membrane transport. III. Congenital chloride diarrhea. Am J Physiol Gastrointest Liver Physiol 276: G7-G13, 1999.
18. Knickelbein RG, Aronson PS, and Dobbins JW. Membrane distribution of sodium-hydrogen and chloride-bicarbonate exchangers in crypt and villus cell membranes from rabbit ileum. J Clin Invest 82: 2158-2163, 1988.
19. Knickelbein R and Dobbins JW. Sulfate and oxalate exchange for bicarbonate across the basolateral membrane of rabbit ileum. Am J Physiol Gastrointest Liver Physiol 259: G807-G813, 1990.
20. Knickelbein RG, Aronson PS, and Dobbins JW. Substrate and inhibitor specificity of anion exchanger on the brush border membrane of rabbit ileum. J Membr Biol 88: 199-204, 1985.
21. Mahajan RJ, Baldwin ML, Harig JM, Ramaswamy K, and Dudeja PK. Chloride transport in human proximal colonic apical membrane vesicles. Biochim Biophys Acta 1280: 12-18, 1996.
22. Melvin JE, Park K, Richardson L, Schultheis PJ, and Shull GE. Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger. J Biol Chem 274: 22855-22861, 1999
23. Moseley RH, Hoglund P, Wu GD, Silberg DG, Haila S, Chapelle ADL, Holmberg C, and Kere J. Downregulated in adenoma gene encodes a chloride transporter defective in congenital chloride diarrhea. Am J Physiol Gastrointest Liver Physiol 267: G185-G192, 1999.
24. Norio R, Perheentupa J, Launiala K, and Hallman N. Congenital chloride diarrhea, an autosomal recessive disease: genetic study of 14 Finnish and 12 other families. Clinical Genet 2: 182-192, 1971.
25. Olsnes S, Tonnessen TI, Ludt J, and Sandvig K. Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines. Biochemistry 26: 2778-2785, 1987.
26. Pilarska M, Wrzosek A, Pikula S, and Famulski KS. Thyroid hormones control lipid composition and membrane fluidity of skeletal muscle sarcolemma. Biochim Biophys Acta 1068: 167-173, 1991.
27. Pinto M, Robine-leon S, and Tappay M. Enterocyte-like differentiation and polarization of the human colon cell line Caco2 in culture. Bio Cell 47: 323-330, 1983.
28. - uptake in apical membrane vesicles of rat distal colon. Am J Physiol Gastrointest Liver Physiol 264: G874-G879, 1993.
29. 3 antiport systems in human ileal brush border membrane vesicles. Ann NY Acad Sci 574: 128-130, 1989.
30. Ribeiro RC, Apriletti JW, West BL, Wagner RL, Fletterick RJ, Schaufele F, and Baxter JD. The molecular biology of thyroid hormone action. Ann NY Acad Sci 758: 366-389, 1995.
31. Robinson R, Robinson LJ, James DE, and Lawrence JC Jr. Glucose transport in L6 myoblasts overexpressing GLUT1 and GLUT4. J Biol Chem 268: 22119-22126, 1993.
32. Ruggiero FM, Landriscina C, Gnoni GV, and Quagliariello E. Lipid composition of liver mitochondria and microsomes in hyperthyroid rats. Lipids 19: 171-178, 1984.
33. Scaglione-Sewell B, Abraham C, Bissonnette M, Skarosi SF, Hart J, Davidson NO, Wali RK, Davis BH, Sitrin M, and Brasitus TA. Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells. Cancer Res 58: 1074-1081, 1998.
34. 4 OH exchange. Am J Physiol Gastrointest Liver Physiol 249: G607-G613, 1985.
35. Segal JA. Rapid, extranuclear effect of 3,5,3′-triiodothyronine on sugar uptake by several tissues in the rat in vivo. Evidence for a physiological role for the thyroid hormone action at the level of the plasma membrane. Endocrinology 124: 2755-2764, 1989.
36. Segal J and Gordon A. The effect 3,5,3′-triiodo-L-thyronine on the kinetic parameters of sugar transport in cultured chick embryo heart cells. Endocrinology 101: 1468-1474, 1977.
37. Silberg DG, Wang W, Moseley RH, and Traber PG. The down-regulated in adenoma (dra) gene encodes an intestine-specific membrane sulfate transport protein. J Biol Chem 270: 11897-11902, 1995.
38. Tyagi S, Ali MM, Malik P, Layden TJ, Ramaswamy K, and Dudeja PK. Expression of anion exchanger isoform AE-3 along the length of the human gastrointestinal (GI) tract (Abstract). Gastroenterology 110: A369, 1996.
39. Tyagi S, Kavilaveettil RJ, Alsafwah S, Ramaswamy K, and Dudeja PK. Evidence for two distinct transporters involved in chloride absorption in the human colonic apical membrane vesicles (Abstract). Gastroenterology 118: A610, 2000.
40. + exchanger from Caco-2 cells, a human intestinal cell line. Am J Physiol Gastrointest Liver Physiol 261: G229-G238, 1991.