Analgesic and antiinflammatory activities of vernonioside B2 from Vernonia condensata

Phytotherapy Research

Volumn 15, Issue 3, 2001, Pages 263-264

  Valverde, A L ^a   Cardoso, G L C ^a   Pereira, N A ^a   Silva, A J R ^a   Kuster, R M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Analgesic activity; Antiinflammatory activity; Asteraceae; Stigmastane; Vernonia condensata; Vernonioside

Indexed keywords

METHANOL; PLANT EXTRACT; UNCLASSIFIED DRUG; VERNONIA CONDENSATA EXTRACT; VERNONIOSIDE B2;

ANALGESIA; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAZIL; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DOSE RESPONSE; EXTRACTION; IN VIVO STUDY; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PERITONEAL CAVITY; PROTON NUCLEAR MAGNETIC RESONANCE; WRITHING TEST;

ACETIC ACID; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTERACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSIDES; MALE; MICE; PAIN; PAIN MEASUREMENT; PLANT EXTRACTS; PLANTS, MEDICINAL;

ASTERACEAE; VERNONIA; VERNONIA CONDENSATA;

EID: 0034996118     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.733     Document Type: Article

References (9)

1. Bohlmann F, Mueller L, Gupta RK, King RM, Robinson H. 1981. Naturally occurring terpene derivatives. Part 362. Hirsutinolides from Vernonia species. Phytochemistry 20: 2233-2237.
2. Frutuoso VS, Gurjao MRR, Cordeiro RSB, Martins MA. 1994. Analgesic and anti-ulcerogenic effects of a polar extract from leaves of Vernonia condensata. Plants Med 60: 21-25.
3. Gupta MB, Nath R, Srivastava N, Shanker K, Kishor K, Bhargava KP. 1980. Antiinflammatory and antipyretic activities of β-sitosterol. J Med Plant Res 39: 157-163.
4. Jakupovic J, Zdero C, Boeker R, Warning U, Bohlmann F, Jones SB. 1987. Vernocistifolides and other sesquiterpene lactones from Vernonia and related species. Liebigs Ann Chem 2: 111-123.
5. Jisaka M, Ohigashi H, Takegawa K, et al. 1993. Steroid glucosides from Vernonia amygdalina, a possible chimpanzee medicinal plant. Phytochemistry 34: 409-413.
6. Kimura Y, Yasukawa K, Takido M, Akihisa T, Tamura T. 1995. Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Biol Pharm Bull 18: 1617-1619.
7. Magalhães RA, Machado MIL, Matos JA. 1990. Constituintes químicos micromoleculares do gênero Vernonia. XI Simpósio de Plantas Medicinais do Brasil, SPMB, CEARA Abstract 2.24.
8. Tsai PL, Wang JP, Chang CW, Kuo SC, Chao PDL. 1998. Constituents and bioactive principles of Polygonum chinensis. Phytochemistry 49: 1663-1666.
9. Whittle BA. 1964. The use of changes in capillary permeability in mice to distinguish between narcotic and non-narcotic analgesics. Br J Pharmacol 22: 246-253.