Lateral mechanical coupling of stereocilia in cochlear hair bundles

Biophysical Journal

Volumn 80, Issue 6, 2001, Pages 2608-2621

  Langer, Matthias G ^a   Fink, Stefan ^a   Koitschev, Assen ^b   Rexhausen, Ulrich ^b   Hörber, J K Heinrich ^c   Ruppersberg, J Peter ^b  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL ULTRASTRUCTURE; CHANNEL GATING; COCHLEA; CROSS LINKING; HAIR CELL; NONHUMAN; RAT; SIGNAL TRANSDUCTION; STEREOCILIUM;

ANIMALIA;

EID: 0034995773     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76231-5     Document Type: Article

References (42)

1. Binnig, G., C. Gerber, and C. F. Quate. 1986. Atomic force microscope. Phys. Rev. Lett. 56:930-933.
2. Burnham, N. A., D. D. Dominguez, R. L. Mowery, and R. J. Colton. 1990. Probing the surface forces of monolayer films with an atomic-force microscope. Phys. Rev. Lett. 64:193.
3. Cleveland, J. P., S. Manne, D. Bocek, and P. K. Hansma. 1993. A nondestructive method for determining the spring constant of cantilevers for scanning force microscopy. Rev. Sci. Instrum. 64:403-405.
4. Crawford, A. C., and R. Fettiplace. 1985. The mechanical properties of ciliar bundles of turtle cochlear hair cells. J. Physiol. 364:359-379.
5. Denk, W., J. R. Holt, G. M. Shepherd, and D. P. Corey. 1995. Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links. Neuron. 15:1311-1321.
6. Furness, D. N., and C. M. Hackney. 1985. Cross links between the stereocilia in the guinea pig cochlea. Hearing Res. 18:177-188.
7. Furness, D. N., G. P. Richardson, and I. J. Russell. 1989. Stereociliary bundle morphology in organotypic cultures of the mouse cochlea. Hearing Res. 38:95-109.
8. Géléoc, G. S. G., G. W. T. Lennan, G. P. Richardson, and C. J. Kros. 1997. A quantitive comparison of mechanoelectrical transduction in vestibular and auditory hair cells of neonatal mice. Proc. R. Soc. Lond. B. 264: 611-621.
9. Gillespie, P. G. 1995. Molecular machinery of auditory and vestibular transduction. Curr. Opin. Neurobiol. 5:449-455.
10. Göddenhenrich, T., S. Müller, and C. Heiden. 1994. A lateral modulation technique for simultaneous friction and topography measurements with the atomic force microscope. Rev. Sci. Instrum. 65:2870-2873.
11. Hoh, J. H., and C. A. Schoenenberger. 1994. Surface morphology and mechanical properties of MDCK monolayers by scanning force microscopy. J. Cell Sci. 107:1105-1114.
12. Hörber, J. K. H., W. Häberle, F. Ohnesorge, G. Binnig, H. G. Liebich, C. P. Czerny, H. Mahnel, and A. Mayr. 1992. Investigation of living cells in the nanometer regime with the scanning force microscope. Scanning Microsc. 6:919-930.
13. Howard, J., and J. F. Ashmore. 1986. Stiffness of sensory hair bundles in the sacculus of the frog. Hearing Res. 23:93-104.
14. Hudspeth, A. J., and D. P. Corey. 1977. Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proc. Natl. Acad. Sci. U.S.A. 74:2407-2411.
15. Howard, J., and A. J. Hudspeth. 1987. Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell. Proc. Natl. Acad. Sci. U.S.A. 84: 3064-3068.
16. Howard, J., and A. J. Hudspeth. 1988. Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell. Neuron. 1:189-199.
17. Hudspeth, A. J., and V. S. Markin. 1994. The ear's gears: mechanoelectrical transduction by hair cells. Phys. Today. 47:22-28.
18. Jaramillo, F., and A. J. Hudspeth. 1991. Localization of the hair cell's transduction channels at the hair bundle's top by iontophoretic application of a channel blocker. Neuron. 7:409-420.
19. Jaramillo, F., and A. J. Hudspeth. 1993. Displacement-clamp measurement of the forces exerted by gating springs in the hair bundle. Proc. Natl. Acad. Sci. U.S.A. 90:1330-1334.
20. Kros, C. J., A. Rüsch, and G. P. Richardson. 1992. Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea. Proc. R. Soc. Lomd. B Biol. Sci. 22:185-193.
21. Langer, M. G., A. Koitschev, H. Haase, U. Rexhausen, J. K. Hörber, and J. P. Ruppersberg. 2000. Mechanical stimulation of individual stereocilia of living cochlear hair cells by atomic force microscopy. Ultramicroscopy. 82:269-278.
22. Langer, M. G., W. Öffner, H. Wittmann, H. Flösser, H. Schaar, W. Häberle, A. Pralle, J. P. Ruppersberg, and J. K. H. Hörber. 1997. A scanning force microscope for simultaneous force and patch-clamp measurements on living cell tissues. Rev. Sci. Instrum. 68:2583-2590.
23. Lenoir, M., J. L. Puel, and R. Pujol. 1987. Stereocilia and tectorial membrane development in the rat cochlea: a SEM study. Anat. Embryol. 175:477-487.
24. Lim, D. J. 1986. Functional structure of the organ of Corti: a review. Hearing Res. 22:117-146.
25. Markin, V. S. and A. J. Hudspeth. 1995. Gating-spring models of mechanoelectrical transduction by hair cells of the internal ear. Annu. Rev. Biophys. Biomol. Struct. 24:59-83.
26. 2+ concentration on hair-bundle stiffness and gating-spring integrity in hair cells. Proc. Natl. Acad. Sci. U.S.A. 94:11923-11928.
27. Meyer, G., and N. Amer. 1988. Novel optical approach to atomic force microscopy. Appl. Phys. Lett. 53:1054.
28. Pickles, J. O., S. D. Comis, and M. P. Osborne. 1984. Cross links between stereocilia in the guinea-pig organ of Corti, and their possible relation to sensory transduction. Hearing Res. 15:103-112.
29. Pickles, J. O., M. von Perger, G. W. Rouse, and J. Brix. 1991. The development of links between stereocilia in hair cells of the chick basilar papilla. Hearing Res. 54:153-163.
30. Radmacher, M., M. Fritz, C. M. Kacher, J. P. Cleveland, and P. K. Hansma. 1996. Measuring the viscoelastic properties of human platelets with the atomic force microscope. Biophys. J. 70:556-567.
31. Russell, I. J., M. Kössl, and G. P. Richardson. 1992. Nonlinear mechanical responses of mouse cochlear hair bundles. Proc. R. Soc. Lond. B. 250:217-227.
32. Russell, I. J., and G. P. Richardson. 1987. The morphology and physiology of hair cells in organotypic cultures of the mouse cochlea. Hearing Res. 31:9-24.
33. Shroff, S. G., D. R. Saner, and R. Lal. 1995. Dynamic micromechanical properties of cultured rat atrial myocytes measured by atomic force microscopy. Am. J. Physiol. 269:286-292.
34. Siegel, J., J. Witt, N. Venturi, and S. Field. 1995. Compact large-range cryogenic scanner. Rev. Sci. Instrum. 66:2520-2532.
35. Sobkowicz, H. M., B. Bereman, and J. E. Rose. 1975. Organotypic development of the organ of Corti in culture. J. Neurocytol. 4:543-572.
36. Strelioff, D., and Å. Flock. 1984. Stiffness of sensory-cell hair bundles in the isolated guinea pig cochlea. Hearing Res. 15:19-28.
37. Szymko, Y. M., P. S. Dimitri, and J. C. Saunders. 1992. Stiffness of hair bundles in the chick cochlea. Hearing Res. 59:241-249.
38. Tilney, L. G., and M. S. Tilney. 1986. Functional organization of the cytoskeleton. Hearing Res. 22:55-77.
39. Von Békésy, G. 1960. Experiments in Hearing. MacGraw-Hill, New York.
40. Weisenhorn, A. L., P. K. Hansma, T. R. Albrecht, and C. F. Quate. 1989. Forces in atomic force microscopy in air and water. Appl. Phys. Lett. 54:2651-2635.
41. Zhao, Y., E. N. Yamoah, and P. G. Gillespie. 1996. Regeneration of broken tip links and restoration of mechanical transduction in hair cells. Proc. Natl. Acad. Sci. U.S.A. 24:15469-15474.
42. Zine, A., and R. Romand. 1996. Development of the auditory receptors of the rat: a SEM study. Brain Res. 721:49-58.