Release behavior of ketoprofen from poly(acryloyl-L-proline methyl ester) gels having different crosslinked networks

Pharmaceutical Development and Technology

Volumn 6, Issue 2, 2001, Pages 173-179

  Negishi, Munehiro ^a   Hiroki, Akihiro ^b   Horikoshi, Yoichiro ^a   Miyajima, Masaharu ^a   Maekawa, Yasunari ^c   Katakai, Ryoichi ^b   Yoshida, Masaru ^c  

^a ZERIA PHARMACEUTICAL CO LTD   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c TAKASAKI ADVANCED RADIATION RESEARCH INSTITUTE   (Japan)

Author keywords

Acryloyl L proline methyl ester; Drug release; Ketoprofen; Polymer gel; Radiation induced crosslinking; Thermo responsive function

Indexed keywords

KETOPROFEN; POLY(ACRYLOYLPROLINE METHYL ESTER); POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DRUG RELEASE; DRUG SYNTHESIS; GEL; POLYMERIZATION; PRIORITY JOURNAL; TEMPERATURE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; GELS; KETOPROFEN; POLYMERS; PROLINE; SOLUBILITY;

EID: 0034995494     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100000740     Document Type: Article

References (14)

1. Reticulation des polymeres en solution aqueuse par les rayons gamma
2. OH-radical-induced crosslinking and strand breakage of poly(vinyl alcohol) in aqueous solution in the absence and presence of oxygen. A pulse radiolysis and product study
3. Pulse radiolysis of methacryloyl-L-proline methyl ester in dilute aqueous solution
4. Pulse radiolysis of acryloyl-L-proline methyl ester in dilute aqueous solution
5. Polymerization, self-bridging, and degradation of acryloyl- and methacryloyl-L-proline methyl esters induced by radiation and characteristics of gel swelling
6. Simultaneously occurring process of radiation-induced polymerization, crosslinking and degradation of N-isopropylacrylamide
7. Controlled release of 9-β-D-arabinofuranosyladenine from thermo-responsive devices based on acryloyl-L-proline methyl ester
8. Thermo-responsive hydrogels based on acryloyl-L-proline methyl ester and their use as long-acting testosterone delivery systems
9. Study of coil-globule transition and cross-linking of poly(acrytoyl- and methacryloyl-L-proline methyl esters) prepared by radiation-induced polymerization
10. Swelling and ketoprofen release characteristics of thermo- and pH-responsive copolymer gels
11. Effect of surfactants on the volume phase transition of cross-linked poly(acryloyl-L-proline alkylesters)
12. A simple equation for description of solute release 1. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
13. A simple equation for description of solute release 2. Fickian and anomalous release from swellable devices