Platelet-derived growth factor-α receptor-positive oligodendroglia are frequent in multiple sclerosis lesions

Annals of Neurology

Volumn 49, Issue 6, 2001, Pages 776-785

  Maeda, Yasuhiro ^a   Solanky, Mukesh ^a   Menonna, Joseph ^a   Chapin, John ^a   Li, Weiping ^a   Dowling, Peter ^a  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR A;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MULTIPLE SCLEROSIS; NERVE REGENERATION; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ASTROCYTES; AUTOPSY; CELL DIVISION; CELL SIZE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RNA, MESSENGER; STEM CELLS;

EID: 0034994473     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.1015     Document Type: Article

References (45)

1. Signal transduction via platelet-derived growth factor receptors
2. A role for platelet-derived growth factor in normal gliogenesis in the central nervous system
3. Glial cell diversification in the rat optic nerve
4. Type 1 astrocytes and oligodendrocyte-type 2 astrocyte glial progenitors migrate toward distinct molecules
5. Evidence for neuronal regulation of oligodendrocyte development: Cellular localization of platelet-derived growth factor-receptor and A-chain mRNA during cerebral cortex development in the rat
6. In vivo proliferation of oligodendrocyte progenitors expressing PDGF-R during early remyelination
7. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis
8. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
9. Reluctant remyelination: The missing precursors
10. Multiple sclerosis: Remyelination of nascent lesions
11. Oligodendrocytes in the early course of multiple sclerosis
12. Remyelination in multiple sclerosis
13. Multiple sclerosis: Oligodendrocyte survival and proliferation in an active established lesion
14. Multiple sclerosis: Oligodendrocyte proliferation and differentiation in fresh lesions
15. Demyelinating disease
16. Monoclonal antibody Ki-67: Its use in histopathology
17. Cell death and birth in multiple sclerosis brain
18. Defective measles virus in human subacute sclerosing panencephalitis
19. Temporal expression of myelin-specific components in neonatal mouse brain cultures: Evidence that 2′,3′-cyclic nucleotide 3′-phosphodiesterase appears prior to galactocerebroside
20. Morphological, biochemical, and functional characterization of bulk isolated glial progenitor cells
21. Differential regulation of the 2′,3′-cyclic nucleotide 3′-phosphodiesterase gene during oligodendrocyte development
22. Cell death and control of cell survival in the oligodendrocyte lineage
23. The oligodendrocyte and its many cellular processes
24. Roles of platelet-derived growth factor in the developing and mature nervous system
25. Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain
26. Interaction between NG2 proteoglycan and PDGF-receptor on O2A progenitor cells is required for optimal response to PDGF
27. Plasticity in the adult human oligodendrocyte lineage
28. Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts
29. MRI studies of multiple sclerosis: Implications for the natural history of the disease and for monitoring effectiveness of experimental therapies
30. Axon transection in the lesions of multiple sclerosis
31. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis
32. Identification of glial cell proliferation in early multiple sclerosis lesions
33. Do oligodendrocytes divide?
34. Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons
35. Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein
36. Effects of transforming growth factor-beta and platelet-derived growth factor on oligodendrocyte precursors: Insights gained from a neuronal cell line
37. Pre-oligodendrocytes from adult human CNS
38. Identification, isolation, and promotor-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter
39. Isolation and developmental characterization of cerebral cortical multipotent progenitors
40. The origin of remyelinating cells in the central nervous system
41. Survival and differentiation of oligodendrocytes from neural tissue transplanted into newborn mouse brain
42. Transplantation of glial cells in the CNS
43. Repair of myelin disease: Strategies and progress in animal models
44. Protein growth factors as potential therapies for central nervous system demyelinative disorders