The specificity of peptide chain extension by N-carboxyanhydrides

Origins of Life and Evolution of the Biosphere

Volumn 31, Issue 3, 2001, Pages 241-248

  Wen, Ke ^a   Orgel, Leslie E ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Enantiospecificity; N carboxyanhydrides; Peptide elongation

Indexed keywords

ACID ANHYDRIDE; AMINO ACID; IMIDAZOLE DERIVATIVE; N,N CARBONYLDIIMIDAZOLE; N,N-CARBONYLDIIMIDAZOLE; OLIGOPEPTIDE;

ORIGIN OF LIFE;

AMINO ACID SEQUENCE; ARTICLE; BIOGENESIS; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RNA TRANSLATION; SOLUTION AND SOLUBILITY; SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANHYDRIDES; BIOGENESIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMIDAZOLES; OLIGOPEPTIDES; PEPTIDE CHAIN ELONGATION, TRANSLATIONAL; SOLUTIONS;

EID: 0034992907     PISSN: 01696149     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010651618537     Document Type: Article

References (8)

1. The complete atomic structure of the large ribosomal subunit at 2.4 a resolution
2. Selective emergence and survival of early polypeptides in water
3. Reactions of carbamylimidazoles with nucleophiles - An example of an intramolecular acyl transfer reaction
4. Reactions of polyfunctional amino acids with N,N′-Carbonyldiimidazole in aqueous solution-oligopeptide formation
5. N, N′-Carbonyldiimidazole-induced peptide formation in aqueous solution
6. Racemic origins of the stereochemically homogeneous biosphere. Biased stereoselectivities in the formation of oligomeric peptides