Introduction of single base subtitutions at homologous chromosomal sequences by adeno-associated virus vectors

Molecular Therapy

Volumn 3, Issue 4, 2001, Pages 526-530

  Inoue, Naoki ^a   Dong, Rong ^a   Hirata, Roli K ^a   Russell, David W ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

AAV; Gene targeting; Mismatch; Mutation; Substitution; Vector

Indexed keywords

ALKALINE PHOSPHATASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; VIRUS VECTOR;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; DNA INTEGRATION; DNA REPAIR; EPISOME; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; GENETIC DISORDER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE;

EID: 0034991469     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0283     Document Type: Article

References (22)

1. Human gene targeting by viral vectors
2. High-fidelity correction of mutations at multiple chromosomal positions by adeno-associated virus vectors
3. Design and packaging of adeno-associated virus gene targeting vectors
4. Packaging cells based on inducible gene amplification for the production of adeno-associated virus vectors
5. Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats
6. Rapid and efficient site-specific mutagenesis without phenotypic selection
7. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
8. Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus
9. Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus
10. Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system
11. A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina
12. Detection of deletions and point mutations
13. Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene
14. Spectrum of X-ray-induced mutations in the human hprt gene
15. Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families
16. Evidence for a single-stranded adenovirus-associated virus genome: Formation of a DNA density hybrid on release of viral DNA
17. Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells
18. Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
19. Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells
20. Localization of loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase and biochemical evidence of nonrandom X chromosome expression from studies of a human X-autosome translocation
21. Fine structure of the human hypoxanthine phosphoribosyltransferase gene