Urethra is more sensitive to ischemia than bladder: Evidence from an in vitro rat study

Journal of Urology

Volumn 165, Issue 6 I, 2001, Pages

  Bratslavsky, G ^a   Kogan, B ^a   Levin, R M ^a  

^a STRATTON VA MEDICAL CENTER   (United States)

Author keywords

Anoxia; Bladder; Ischemia; Rats, Sprague Dawley; Urethra

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; BLADDER DISEASE; BLADDER DYSFUNCTION; BLADDER MUSCLE; CONTROLLED STUDY; DETRUSOR MUSCLE; MALE; MUSCLE EXCITATION; MUSCLE ISCHEMIA; MUSCLE PERFUSION; NEUROGENIC BLADDER; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION; REPERFUSION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE TONE; URETHRA DISEASE; URINE INCONTINENCE; ANIMAL; IN VITRO STUDY; ISCHEMIA; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; URETHRA; URODYNAMICS; VASCULARIZATION;

ANIMALS; ISCHEMIA; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RATS; RATS, SPRAGUE-DAWLEY; URETHRA; URODYNAMICS;

EID: 0034991082     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)66299-4     Document Type: Article

References (40)

1. Pharmacology of lower urinary tract smooth muscles and penile erectile tissues
2. Voiding function and dysfunction: Relevant anatomy, physiology, pharmacology, and molecular aspects
3. In vitro studies of glucose metabolism of the rabbit urinary bladder
4. Energy expenditure of longitudinal smooth muscle of rabbit urinary bladder
5. Metabolism and force in hypertrophic smooth muscle from rat urinary bladder
6. Chemical energetics of force development, force maintenance, and relaxation in mammalian smooth muscle
7. Chemical energetics of contraction in mammalian smooth muscle
8. Smooth muscle energetics
9. Comparison of the contractile and metabolic effects of muscarinic stimulation with those of KCl
10. Effect of bethanechol on glycolysis and high energy phosphate metabolism of the rabbit urinary bladder
11. Dissociation of the metabolic response from the contractile response to muscarinic receptor stimulation in the rabbit urinary bladder
12. Canine bladder blood flow and oxygenation: Changes induced by filling, contraction and outlet obstruction
13. The effect of bladder outlet obstruction on tissue oxygen tension and blood flow in the pig bladder
14. Blood flow of the urinary bladder. Effects of outlet obstruction and correlation with bioenergetic metabolism
15. Effect of chronic bladder outlet obstruction on the blood flow of the rabbit bladder
16. Urinary bladder blood flow changes during the micturition cycle in a conscious pig model
17. Effects of outlet obstruction and its reversal on mitochondrial enzyme activity in rabbit urinary bladders
18. Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit
19. The effects of short-term in vivo ischemia on the contractile function of the rabbit urinary bladder
20. Effects of in vivo ischemia on contractile responses of rabbit bladder to field stimulation, carbachol, ATP, and KCl
21. Rabbit vs. rat urinary bladder: Effects of in vitro hypoxia
22. Comparative physiology and biochemistry of the rat and rabbit urinary bladder
23. Effect of repetitive stimulation on the contractile response of rabbit urinary bladder subjected to in vitro hypoxia or in vitro ischemic followed by reoxygenation
24. The contractile and metabolic effects of acute ischemia upon the rabbit urinary bladder
25. Effects of ischemia on the function of the isolated rat detrusor muscle
26. The effect of anoxia and glucose-free solutions on the contractile response of guinea-pig detrusor strips to intrinsic nerve stimulation and the application of excitatory agonists
27. Genetic and cellular characteristics of bladder outlet obstruction
28. Effect of bladder outflow obstruction on the innervation of the rabbit urinary bladder
29. Physiology and pharmacology of the bladder and urethra
30. Bladder and urethral responses to sympathetic stimulation
31. 2+ ATPase in rabbit bladder muscle and mucosa: Effects of urinary outlet obstruction
32. The decompensated detrusor II: Evidence for loss of sarcoplasmic reticulum function after bladder outlet obstruction in the rabbit
33. Calcium-mediated cell injury and cell death
34. Calcium channel antagonists prevent urinary bladder growth and neuroplasticity following mechanical stress
35. Correlation of EGTA and calcium-blocking agents on the response of the bladder to in vitro ischemia
36. Correlation of ischemia/reperfusion or partial outlet obstruction-induced spectrin proteolysis by calpain with contractile dysfunction in rabbit bladder
37. Oxygen free radicals induced lipid peroxidation in overdistention of the rabbit urinary bladders
38. Correlation of lipid peroxidation with energetic metabolism and contractile function in overdistention of the rabbit urinary bladder
39. The in vivo and in vitro effects of hypoxia on pig urethral smooth muscle