Gene transfer to blood vessels: A research tool and potential therapy

American Journal of Hypertension

Volumn 14, Issue 6 II, 2001, Pages

  Heistad, Donald D ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cerebral vasospasm; Gene therapy; Pulmonary hypertension; Vascular biology

Indexed keywords

BRAIN VASOSPASM; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; GENE THERAPY; GENE TRANSFER; HUMAN; HYPERCHOLESTEROLEMIA; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SUBARACHNOID HEMORRHAGE; VASOMOTOR REFLEX;

EID: 0034990235     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0895-7061(01)02066-0     Document Type: Conference Paper

References (34)

1. Site-specific gene expression in vivo by direct gene transfer into the arterial wall
2. Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
3. The advent of adenovirus: Gene therapy for cardiovascular disease
4. Adenovirus-mediated gene transfer in vivo to cerebral blood vessels and perivascular tissue in mice
5. Altered vascular function following adenovirus-mediated overexpression of endothelial nitric oxide synthase
6. Adventitial expression of recombinant eNOS gene restores NO production in arteries without endothelium
7. Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation and neointima hyperplasia
8. Gene therapy inhibiting neointimal vascular lesion: In vivo transfer of endothelial cell nitric oxide synthase gene
9. Adenovirus-mediated gene transfer to cerebral blood vessels in vivo
10. Adenovirus-mediated gene transfer to normal and atherosclerotic vessels: A novel approach
11. Gene transfer of calcitonin gene-related peptide to cerebral arteries
12. Gene transfer to carotid sinus in vivo: A novel approach to investigation of baroreceptors
13. Effects of in vivo adventitial expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries
14. Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice
15. Gene transfer of eNOS reduces angiotensin II-induced endothelial dysfunction
16. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
17. Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits
18. Improvement of relaxation in an atherosclerotic artery by gene transfer of endothelial nitric oxide synthase
19. Adenoviral-mediated gene transfer of inducible NO synthase alters vascular function
20. Gene transfer of CGRP prevents vasoconstriction after subarachnoid hemorrhage
21. Adenoviral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats
22. Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo: Effect on agonist-induced and flow-mediated vascular responses
23. In vivo gene transfer of prepro calcitonin gene-related peptide (CGRP) to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse
24. Prospects for genetic therapy for cardiovascular disease
25. Genomic DNA transfer with a high capacity adenoviral vector results in improved in vivo gene expression and decreased toxicity
26. Endothelium-specific in vivo gene transfer
27. Polymer and lipids enhance adenovirus-mediated gene transfer to rabbit carotid artery
28. Approaches to enhance expression after adenovirus-mediated gene transfer to carotid artery
29. Calcium phosphate precipitates augment adenovirus-mediated gene transfer to blood vessel in vitro and in vivo
30. Augmented adenovirus-mediated gene transfer to atherosclerotic vessels
31. Adenovirus-mediated gene transfer is augmented in basilar and carotid arteries of heritable hyperlipidemic rabbits
32. Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats
33. Is gene therapy for hypertension possible?