The 2.2 å crystal structure of Hsp33: A heat shock protein with redox-regulated chaperone activity

Structure

Volumn 9, Issue 5, 2001, Pages 367-375

  Vijayalakshmi, J ^a   Mukhergee, Matthew K ^a   Graumann, Johannes ^a   Jakob, Ursula ^a   Saper, Mark A ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Crystal structure; Dimerization; Heat shock protein; Hsp33; Oxidative stress; Zinc

Indexed keywords

CHAPERONE; DIMER; GLUTAMIC ACID; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 33; MONOMER; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ZINC; BACTERIAL PROTEIN; ESCHERICHIA COLI PROTEIN; HSP33 PROTEIN, BACTERIA; HSP33 PROTEIN, E COLI;

ARTICLE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HEAT-SHOCK PROTEINS; MODELS, MOLECULAR; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 0034990115     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00597-4     Document Type: Article

References (27)

1. Supervising the fold: Functional principles of molecular chaperones
2. Hsp26: A temperature-regulated chaperone
3. Redox switch of Hsp33 has a novel zinc-binding motif
4. Mass spectrometry unravels disulfide bond formation as the mechanism that activates a molecular chaperone
5. Chaperone activity with a redox switch
6. Activation of the redox-regulated molecular chaperone Hsp33-a two step mechanism
7. Protein structure comparison by alignment of distance matrices
8. Surprising similarities in structure comparison
9. The structure and function of the aspartic proteinases
10. The structural basis for the oriented assembly of a TBP/TFB/promoter complex
11. 3D domain swapping: A mechanism for oligomer assembly
12. Combining evolutionary information and neural networks to predict protein secondary structure
13. The crystal structure of a GroEL/peptide complex: Plasticity as a basis for substrate diversity
14. NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: A preview of chaperone-protein interaction
15. Processing of X-ray diffraction data collected in oscillation mode
16. The CCP4 suite programs for protein crystallography
17. Automated MAD and MIR structure solution
18. Improved methods for binding protein models in electron density maps and the location of errors in these models
19. Crystallography & NMR system: A new software suite for macromolecular structure determination
20. Improved Fourier coefficients for maps using phases from partial structures with errors
21. Protein sequence alignments: A strategy for the hierarchical analysis of residue conservation
22. Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
23. Ribbons
24. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
25. SURFNET: A program for visualizing molecular surfaces, cavities, and intermolecular interactions