Syntheses of two deacetyl-thymosin β4 analogs and their anti-inflammatory effect on carrageenin-induced edema in the mouse paw

Mediators of Inflammation

Volumn 10, Issue 2, 2001, Pages 89-92

  Abiko, T ^a   Ogawa, R ^a  

^a Global Shinwa Pharmaceut Co Ltd   (Japan)

Author keywords

Met(0)6 deacetyl thymosin 4 analogue synthesis; Anti inflammatory effect; Carrageenin induced edema; Mouse paw

Indexed keywords

9 FLUORENYLMETHYL CHLOROFORMATE; [6 METHIONINE SULFOXIDE,12 (4 FLUOROPHENYLALANINE)]DEACETYLTHYMOSIN BETA4; [6 METHIONINE SULFOXIDE,12 METHYLTYROSINE]DEACETYLTHYMOSIN BETA4; [6 METHIONINE SULFOXIDE]DEACETYLTHYMOSIN BETA4; ANTIINFLAMMATORY AGENT; CARRAGEENAN; SYNTHETIC PEPTIDE; THYMOSIN BETA4; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOASSAY; DRUG SYNTHESIS; EDEMA; EXPERIMENTAL MODEL; FLUORINATION; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; HINDLIMB; MICE; MICE, INBRED BALB C; THYMOSIN;

ANIMALIA;

EID: 0034989651     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629350120054563     Document Type: Article

References (5)

1. 4: A thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations
2. 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoides
3. 4: Synthesis and effect on the impaired peripheral T-cell subsets in patients with chronic renal failure
4. 4 in the impaired blastogenic response of uremic T-lymphocytes
5. A nitric oxide synthase inhibitor reduces inflammation, downregulates inflammatory cytokines and enhances interleukin-10 production in carrageenan induced oedema in mice