Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is membrane-bound ubiquitin ligase

Journal of Cell Science

Volumn 114, Issue 10, 2001, Pages 1949-1957

  Matsuda, N ^a   Suzuki, T ^a   Tanaka, K ^a   Nakano, A ^a  

^a RIKEN   (Japan)

Author keywords

E3; Membrane anchor; RING finger; Sec15; Ubiquitination

Indexed keywords

ENZYME; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE;

ARABIDOPSIS; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENZYME SUBSTRATE; GENE MUTATION; GENETIC CONSERVATION; HUMAN; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN MODIFICATION; PROTEIN MOTIF; RABBIT; RETICULOCYTE; WHEAT GERM;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARRIER PROTEINS; CLONING, MOLECULAR; CONSERVED SEQUENCE; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; LIGASES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PLASMIDS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0034989296     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (72)

1. Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport
2. The Rho GTPase Rho3 has a direct role in exocytosis that is distinct from its role in actin polarity
3. The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways
4. Molecular interaction between COP1 and HY5 defines a regulatory switch for light control of Arabidopsis development
5. Use of a reporter transgene to generate Arabidopsis mutants in ubiquitin-dependent protein degradation
6. The recognition component of the N-end rule pathway
7. UPL1 and 2, two 405 kDa ubiquitin- protein ligases from Arabidopsis thaliana related to the HECT-domain protein family
8. Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation
9. Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins
10. Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis
11. Ubiquitin-mediated proteolysis: Biological regulation via destruction
12. Membrane topology and function of Der3/Hrd1p as an ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation
13. Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
14. COP1, an Arabidopsis regulatory gene, encodes a protein with both a Zinc-binding motif and a Gβ homologous domain
15. SCF and Cullin/RING-H2-based ubiquitin-ligases
16. COP1 patrols the night beat
17. A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes
18. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
19. A novel cystine-rich sequence motif
20. Ubiquitination: RING for destruction?
21. Homologs of the essential ubiquitin conjugating enzymes UBC1, 4, and 5 in yeast are encoded by a multigene family in Arabidopsis thaliana
22. The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex
23. Function of the ubiquitin-proteasome pathway in auxin response
24. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein
25. The cell biology of the COP/DET/FUS proteins. Regulating proteolysis in photomorphogenesis and beyond?
26. Ubiquitin-dependent proteolytic pathway in wheat germ: Isolation of multiple forms of ubiquitin-activating enzyme, E1
27. Proposed role of ATP in protein breakdown: Conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis
28. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
29. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
30. Identification of the von Hippel-Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
31. The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
32. SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast
33. Widespread occurrence of a highly conserved RING-H2 zinc finger motif in the model plant Arabidopsis thaliana
34. Biogenesis of the protein storage vacuole crystalloid
35. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase
36. RING finger proteins: Mediators of ubiquitin ligase activity
37. A human ubiquitin-conjugating enzyme homologous to yeast UBC8
38. Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme
39. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase
40. Impaired proteasome function rescues thermosensitivity of yeast cells lacking the coatomer subunit ε-COP
41. Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity
42. The mouse and human genes encoding the recognition component of the N-end rule pathway
43. The APC11 RING-H2 finger mediates E2-dependent ubiquitination
44. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
45. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
46. RMA1, an Arabidopsis thaliana gene whose cDNA suppresses the yeast sec15 mutation, encodes a novel protein with a RING finger motif and a membrane anchor
47. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity
48. Targeted destabilization of HY5 during light-regulated development of Arabidopsis
49. The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl
50. Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast
51. PRT1 of Arabidopsis thaliana encodes a component of the plant N-end rule pathway
52. Reconstitution of p53-ubiquitinylation reactions from purified components: The role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP)
53. Early elicitor induction in members of a novel multigene family coding for highly related RING-H2 proteins in Arabidopsis thaliana
54. A ras-like protein is required for a post-Golgi event in yeast secretion
55. Does this have a familiar RING?
56. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
57. Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
58. Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins
59. Familial Parkinson disease gene product, Parkin, is a ubiquitin-protein ligase
60. Grr1 and Rbx1
61. Requirement of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha
62. Yeast protein translocation complex: Isolation of two genes SEB1 and SEB2 encoding proteins homologous to the Sec61 beta subunit
63. The RING finger motif of photomorphogenic repressor COP1 specifically interacts with the RING-H2 motif of a novel Arabidopsis protein
64. Proteolysis and the cell cycle: With this RING I do thee destroy
65. Polypeptide tags, ubiquitous modifiers for plant protein regulation
66. The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae
67. Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes
68. Ubiquitin system: Selectivity and timing of protein destruction
69. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
70. Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7
71. Mass spectromeric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to Cullins
72. Cloning and molecular characterization of an Arabidopsis thaliana RING zinc finger gene expressed preferentially during seed development